Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 8/20 | 0.45 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242893 | 0.83 | LMNA (0.49) | CYP3A4ACHEBCHEFAAHALDH1A1 | |
| SCHEMBL2493638 | 0.82 | MEN1 (0.51) | CYP3A4BCHEALDH1A1TSHRMEN1 | |
| SCHEMBL3884098 | 0.82 | MEN1 (0.61) | CYP3A4TP53ACHEBCHEFAAH | |
| SCHEMBL27766267 | 0.82 | KMT2A (0.50) | BCHEALDH1A1MEN1KMT2A | |
| SCHEMBL28868300 | 0.81 | MEN1 (0.44) | ACHEBCHEFAAHALDH1A1MEN1 | |
| SCHEMBL29228866 | 0.81 | ACHE (0.49) | CYP3A4ACHEBCHEFAAH | |
| SCHEMBL27410608 | 0.81 | ACHE (0.44) | CYP3A4ACHEBCHEFAAHMEN1 | |
| SCHEMBL29130421 | 0.81 | BCHE (0.46) | ACHEBCHEFAAHALDH1A1MEN1 | |
| SCHEMBL28941287 | 0.79 | LMNA (0.42) | ACHEALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL28941154 | 0.78 | MEN1 (0.41) | ACHEBCHEALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1098841-C | Novel amide derivatives and pharmaceutical compositions thereof | YAMANOUCHI PHARMA CO LTD (JP) | 2003-01-15 | — | — | CN | disclosed |
| CN-1244193-A | Novel amide derivatives and medicinal compositions thereof | YAMANOUCHI PHARMA CO LTD (JP) | 2000-02-09 | — | — | CN | disclosed |