Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27774480 | 0.81 | MEN1 (0.53) | KMT2AMEN1ELANERAB9ASMN1; SMN2 | |
| SCHEMBL27578920 | 0.80 | MEN1 (0.51) | KMT2AMEN1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL12086366 | 0.80 | KMT2A (0.51) | KMT2AMEN1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL2493638 | 0.80 | MEN1 (0.51) | KMT2AMEN1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL27766267 | 0.80 | KMT2A (0.50) | KMT2AMEN1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL27969685 | 0.75 | GAA (0.61) | KMT2AMEN1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL28868300 | 0.73 | MEN1 (0.44) | KMT2AMEN1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL29130421 | 0.73 | BCHE (0.46) | KMT2AMEN1RAB9ASMN1; SMN2BCHE | |
| SCHEMBL27864656 | 0.73 | KMT2A (0.58) | KMT2AELANERAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL6794454 | 0.72 | LMNA (0.55) | KMT2AMEN1ELANERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567503-A1 | PYRAZOLE DERIVATIVES USEFUL AS COX-I INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050632-A1 | PYRAZOLE DERIVATIVES USEFUL AS COX-I INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-17 | — | — | WO | disclosed |