Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | ME2 | P23368 | 1/20 | 0.52 |
| ▸ | ME1 | P48163 | 1/20 | 0.52 |
| ▸ | ME3 | Q16798 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | PHGDH | O43175 | 2/20 | 0.48 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27664248 | 0.86 | AKR1C3 (0.85) | AKR1C3CA12CA2CA9ME2 | |
| SCHEMBL24937721 | 0.81 | AKR1C3 (0.63) | AKR1C3SMN1; SMN2MAPT | |
| SCHEMBL24937183 | 0.81 | AKR1C3 (0.65) | AKR1C3ME2ME1ME3TRPV1 | |
| SCHEMBL24937831 | 0.80 | L3MBTL1 (0.58) | — | |
| SCHEMBL24937848 | 0.80 | AKR1C3 (0.61) | AKR1C3CA12CA2CA9ME2 | |
| SCHEMBL1458650 | 0.79 | CA12 (0.71) | AKR1C3CA12CA2CA9ME2 | |
| SCHEMBL2404063 | 0.77 | CA12 (0.69) | AKR1C3CA12CA2CA9ME2 | |
| SCHEMBL5542076 | 0.77 | CA12 (0.69) | AKR1C3CA12CA2CA9ME2 | |
| SCHEMBL30807959 | 0.77 | CA12 (0.69) | AKR1C3CA12CA2CA9ME2 | |
| SCHEMBL24937782 | 0.77 | KDM4E (0.50) | AKR1C3SMN1; SMN2SLC6A7SLC6A9SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230024778-A1 | STRIGOLACTONE RECEPTOR INHIBITOR, AGRICULTURAL COMPOSITION AND USE THEREOF, STRIGA SEED GERMINATION INHIBITOR, AND TRIAZOLE UREA COMPOUND | THE UNIVERSITY OF TOKYO (JP) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024778-A1 | STRIGOLACTONE RECEPTOR INHIBITOR, AGRICULTURAL COMPOSITION AND USE THEREOF, STRIGA SEED GERMINATION INHIBITOR, AND TRIAZOLE UREA COMPOUND | UTS2R, TAS1R1, ULK3 | AKR1C3 689/4885CA12 4770/4885CA2 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.