Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936951 | 0.86 | TYR (0.44) | CYP19A1KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9937684 | 0.82 | TYR (0.47) | CYP19A1KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9938471 | 0.79 | CYP19A1 (0.41) | CYP19A1KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9969790 | 0.78 | ALDH1A1 (0.42) | KMT2ASMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL9968851 | 0.76 | ALDH1A1 (0.41) | KMT2ASMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL9937177 | 0.73 | L3MBTL1 (0.40) | KMT2AMEN1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9937665 | 0.73 | TSHR (0.41) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL9937503 | 0.73 | ALDH1A1 (0.39) | KMT2ASMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL9937438 | 0.72 | ALDH1A1 (0.39) | KMT2ASMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL16530037 | 0.72 | L3MBTL1 (0.46) | CYP19A1KMT2ASMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3393603-B1 | TOPICAL DELIVERY SYSTEM FOR ACTIVE INGREDIENTS | OREAL (FR) | 2023-01-18 | — | — | EP | disclosed |