SCHEMBL9936951

SCHEMBL9936951

CCCCN1C(=O)CC(Cc2ccc(O)cc2O)C1=O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.44
CYP19A1 P11511 4/20 0.43
KMT2A Q03164 3/20 0.43
TSHR P16473 3/20 0.43
MEN1 O00255 2/20 0.43
MAPT P10636 2/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
ALOX5 P09917 1/20 0.43
ALOX15 P16050 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 6/20 0.40
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPK1 P28482 1/20 0.37
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9937684 0.95 TYR (0.47) TYRCYP19A1KMT2ATSHRMEN1
SCHEMBL9938471 0.93 CYP19A1 (0.41) TYRCYP19A1KMT2ATSHRMEN1
SCHEMBL9969790 0.92 ALDH1A1 (0.42) TYRKMT2ATSHRMEN1MAPT
SCHEMBL9968851 0.90 ALDH1A1 (0.41) TYRKMT2ATSHRMEN1MAPT
SCHEMBL9937177 0.87 L3MBTL1 (0.40) TYRKMT2ATSHRMEN1MAPT
SCHEMBL24937253 0.86 CYP19A1 (0.40) TYRCYP19A1KMT2ATSHRMEN1
SCHEMBL9937438 0.86 ALDH1A1 (0.39) TYRKMT2ATSHRMEN1MAPT
SCHEMBL9937665 0.86 TSHR (0.41) KMT2ATSHRMEN1ALDH1A1L3MBTL1
SCHEMBL9937503 0.86 ALDH1A1 (0.39) KMT2ATSHRMEN1MAPTSMN1; SMN2
SCHEMBL9936606 0.85 TNF (0.43) TSHRALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2651886-B1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES ORÉAL L (FR) 2015-03-04 EP claimed
US-8937187-B2 Method for depigmenting keratin materials using resorcinol derivatives L'OREAL (FR) 2015-01-20 US claimed
US-20130281507-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2013-10-24 US claimed
EP-2651886-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'Oréal (FR) 2013-10-23 EP claimed
WO-2012079938-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2012-06-21 WO claimed
EP-3393603-B1 TOPICAL DELIVERY SYSTEM FOR ACTIVE INGREDIENTS OREAL (FR) 2023-01-18 EP disclosed
US-11260000-B2 Composition in the form of nano or micro emulsion or with lamellar structure L'OREAL (FR) 2022-03-01 US disclosed
US-11154473-B2 Composition comprising resorcinol or derivative thereof L'OREAL (FR) 2021-10-26 US disclosed
US-11154473-B2 Composition comprising resorcinol or derivative thereof L'OREAL (FR) 2021-10-26 US disclosed
EP-3171853-B1 COMPOSITION IN THE FORM OF NANO OR MICRO EMULSION OR WITH LAMELLAR STRUCTURE OREAL (FR) 2020-07-29 EP disclosed
EP-3171853-B1 COMPOSITION IN THE FORM OF NANO OR MICRO EMULSION OR WITH LAMELLAR STRUCTURE OREAL (FR) 2020-07-29 EP disclosed
US-20190336421-A1 COMPOSITION COMPRISING RESORCINOL OR DERIVATIVE THEREOF L'OREAL (FR) 2019-11-07 US disclosed
US-8937187-B2 Method for depigmenting keratin materials using resorcinol derivatives L'OREAL (FR) 2015-01-20 US disclosed
US-8937187-B2 Method for depigmenting keratin materials using resorcinol derivatives L'OREAL (FR) 2015-01-20 US disclosed
US-20130281507-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2013-10-24 US disclosed
US-20130281507-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2013-10-24 US disclosed
US-20130281507-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2013-10-24 US disclosed
EP-2651886-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'Oréal (FR) 2013-10-23 EP disclosed
WO-2012079938-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2012-06-21 WO disclosed
WO-2012079938-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2012-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11154473-B2 Composition comprising resorcinol or derivative thereof NQO1, LRAT, RBP4 TYR 4/4885CYP19A1 20/4885KMT2A 1778/4885
US-20190336421-A1 COMPOSITION COMPRISING RESORCINOL OR DERIVATIVE THEREOF NQO1, LRAT, RBP4 TYR 4/4885CYP19A1 20/4885KMT2A 1778/4885
US-20130281507-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES KRT18, KLHL20, IK TYR 9/4885CYP19A1 672/4885KMT2A 144/4885
US-11260000-B2 Composition in the form of nano or micro emulsion or with lamellar structure LRAT, LIPA, DAGLA TYR 194/4885CYP19A1 677/4885KMT2A 2431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.