Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28187100 | 0.86 | MAPT (0.48) | USP2MAPTTP53L3MBTL1GAA | |
| SCHEMBL25392854 | 0.86 | USP2 (0.40) | MAPK10USP2CYP11B1CYP11B2MAPT | |
| SCHEMBL28673167 | 0.85 | USP2 (0.55) | MAPK10USP2CYP11B1CYP11B2CCNC | |
| SCHEMBL24936716 | 0.83 | CCNC (0.49) | MAPK10USP2CCNCCDK8HDAC3 | |
| SCHEMBL24435291 | 0.82 | MAPK10 (0.52) | MAPK10USP2CYP11B1CYP11B2CCNC | |
| SCHEMBL16116241 | 0.78 | CCNC (0.71) | MAPK10USP2CYP11B1CYP11B2CCNC | |
| SCHEMBL28683880 | 0.76 | CYP11B1 (0.70) | MAPK10USP2CYP11B1CYP11B2HDAC3 | |
| SCHEMBL25395065 | 0.76 | USP2 (0.51) | MAPK10USP2CYP11B1CYP11B2HDAC3 | |
| SCHEMBL25374599 | 0.76 | USP2 (0.41) | MAPK10USP2CYP11B1CYP11B2MAPT | |
| SCHEMBL25373841 | 0.74 | LOXL2 (0.39) | MAPK10USP2CYP11B1CYP11B2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999256-A | Protein secretion inhibitor | 分子门生物科技公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023010051-A1 | PROTEIN SECRETION INHIBITORS | GATE BIOSCIENCE, INC. (US) | 2023-02-02 | — | — | WO | disclosed |