Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DNM1L | O00429 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24937330 | 0.85 | MAPK10 (0.54) | USP2MAPK10GAAL3MBTL1NPSR1 | |
| SCHEMBL24435291 | 0.83 | MAPK10 (0.52) | USP2MAPK10GAAL3MBTL1NPSR1 | |
| SCHEMBL16116241 | 0.79 | CCNC (0.71) | USP2MAPK10NPSR1CYP11B1CYP11B2 | |
| SCHEMBL25395065 | 0.77 | USP2 (0.51) | USP2MAPK10CYP11B1CYP11B2HDAC3 | |
| SCHEMBL28683880 | 0.77 | CYP11B1 (0.70) | USP2MAPK10CYP11B1CYP11B2TSHR | |
| SCHEMBL24434966 | 0.75 | RAB9A (0.58) | USP2MAPK10GAAL3MBTL1NPSR1 | |
| SCHEMBL28689329 | 0.74 | MEN1 (0.49) | USP2MAPK10GAAL3MBTL1NPSR1 | |
| SCHEMBL1562627 | 0.73 | SMN1; SMN2 (0.54) | GAAMAPTTSHRLMNAKDM4E | |
| SCHEMBL28932115 | 0.73 | MAPK10 (0.50) | USP2MAPK10GAACYP11B1CYP11B2 | |
| SCHEMBL11914100 | 0.73 | ABL1 (0.48) | GAAL3MBTL1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3930849-B1 | THIAZOLE DERIVATIVES AS PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2025-02-19 | — | — | EP | disclosed |
| CN-113993587-A | Thiazole derivatives as protein secretion inhibitors | 科智生命科学公司 | 2022-01-28 | — | — | CN | disclosed |