Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | MARS1 | P56192 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25394318 | 0.84 | LOXL2 (0.41) | CCNCCDK8KDM4AKDM5AKDM4C | |
| SCHEMBL24937330 | 0.83 | MAPK10 (0.54) | CCNCCDK8MEN1KMT2AUSP2 | |
| SCHEMBL16115375 | 0.77 | CCNC (0.80) | CCNCCDK8KDM4EGSK3BDYRK1A | |
| SCHEMBL25374991 | 0.73 | CHRM1 (0.41) | CCNCCDK8KDM4AKDM5AKDM4C | |
| SCHEMBL7488391 | 0.73 | CYP11B1 (0.47) | CCNCCDK8MEN1KMT2AMARS1 | |
| SCHEMBL24434943 | 0.73 | KDM4E (0.49) | CCNCCDK8MEN1KMT2AMARS1 | |
| SCHEMBL31596888 | 0.71 | CHRM1 (0.41) | CCNCCDK8KDM4AKDM5AKDM4C | |
| SCHEMBL28187100 | 0.71 | MAPT (0.48) | MEN1KMT2AUSP2CNR2CYP1A2 | |
| SCHEMBL25392034 | 0.71 | LOXL2 (0.40) | CCNCCDK8MEN1KMT2AKDM4A | |
| SCHEMBL2895007 | 0.71 | CCR2 (0.70) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999256-A | Protein secretion inhibitor | 分子门生物科技公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023010051-A1 | PROTEIN SECRETION INHIBITORS | GATE BIOSCIENCE, INC. (US) | 2023-02-02 | — | — | WO | disclosed |