Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ME2 | P23368 | 1/20 | 0.46 |
| ▸ | ME1 | P48163 | 1/20 | 0.46 |
| ▸ | ME3 | Q16798 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24937789 | 0.86 | AKR1C3 (0.58) | AKR1C3LMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL24937848 | 0.82 | AKR1C3 (0.61) | AKR1C3SMN1; SMN2TRPV1MAPTME2 | |
| SCHEMBL24937728 | 0.82 | KDM4E (0.47) | AKR1C3 | |
| SCHEMBL24937187 | 0.82 | AKR1C3 (0.60) | AKR1C3GRM5 | |
| SCHEMBL24937862 | 0.81 | AKR1C3 (0.62) | AKR1C3LMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL24937761 | 0.79 | AKR1C3 (0.58) | AKR1C3LMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL24937183 | 0.78 | AKR1C3 (0.65) | AKR1C3LMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL14276932 | 0.75 | CASP6 (0.69) | AKR1C3LMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL5466673 | 0.74 | AKR1C3 (0.73) | AKR1C3LMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL19078787 | 0.74 | AKR1C3 (0.56) | AKR1C3LMNAALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230024778-A1 | STRIGOLACTONE RECEPTOR INHIBITOR, AGRICULTURAL COMPOSITION AND USE THEREOF, STRIGA SEED GERMINATION INHIBITOR, AND TRIAZOLE UREA COMPOUND | THE UNIVERSITY OF TOKYO (JP) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024778-A1 | STRIGOLACTONE RECEPTOR INHIBITOR, AGRICULTURAL COMPOSITION AND USE THEREOF, STRIGA SEED GERMINATION INHIBITOR, AND TRIAZOLE UREA COMPOUND | UTS2R, TAS1R1, ULK3 | AKR1C3 689/4885LMNA 4354/4885ALDH1A1 1950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.