Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20100736 | 0.80 | SMN1; SMN2 (0.44) | GAASMN1; SMN2HPGDNPSR1L3MBTL1 | |
| SCHEMBL20234241 | 0.80 | ALDH1A1 (0.41) | GAASMN1; SMN2HPGDNPSR1L3MBTL1 | |
| SCHEMBL19033101 | 0.79 | SMN1; SMN2 (0.43) | GAASMN1; SMN2HPGDNPSR1L3MBTL1 | |
| SCHEMBL21900547 | 0.77 | GAA (0.39) | GAASMN1; SMN2HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL20234246 | 0.76 | SMN1; SMN2 (0.41) | GAASMN1; SMN2HPGDNPSR1L3MBTL1 | |
| SCHEMBL8600123 | 0.74 | GAA (0.50) | GAASMN1; SMN2CES2CYP4F2CYP4A11 | |
| SCHEMBL8596890 | 0.74 | GAA (0.50) | GAASMN1; SMN2CES2CYP4F2CYP4A11 | |
| SCHEMBL20104859 | 0.72 | ALDH1A1 (0.42) | GAASMN1; SMN2HPGDNPSR1L3MBTL1 | |
| SCHEMBL11617169 | 0.72 | LMNA (0.40) | GAASMN1; SMN2HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL24242137 | 0.71 | SMN1; SMN2 (0.49) | GAASMN1; SMN2HPGDNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119539-A1 | PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF | XWPharma Ltd. (KY) | 2023-01-18 | — | — | EP | disclosed |