Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS7 | Q9UKP4 | 8/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 10/20 | 0.32 |
| ▸ | MMP2 | P08253 | 9/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 8/20 | 0.32 |
| ▸ | MMP3 | P08254 | 8/20 | 0.32 |
| ▸ | MMP13 | P45452 | 8/20 | 0.32 |
| ▸ | MMP14 | P50281 | 8/20 | 0.32 |
| ▸ | MMP1 | P03956 | 6/20 | 0.32 |
| ▸ | MMP9 | P14780 | 6/20 | 0.32 |
| ▸ | MMP7 | P09237 | 5/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.32 |
| ▸ | MMP12 | P39900 | 2/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23354131 | 0.85 | ADAMTS7 (0.43) | ADAMTS7ADAMTS5MMP2ADAMTS4MMP3 | |
| SCHEMBL24927741 | 0.85 | ADAMTS7 (0.41) | ADAMTS7ADAMTS5MMP2ADAMTS4MMP3 | |
| SCHEMBL29873894 | 0.85 | ADAMTS7 (0.41) | ADAMTS7ADAMTS5MMP2ADAMTS4MMP3 | |
| SCHEMBL23366910 | 0.78 | ADAMTS7 (0.35) | ADAMTS7 | |
| SCHEMBL23366931 | 0.76 | ADAMTS7 (0.32) | ADAMTS7 | |
| Hydrochloric Acid SCHEMBL31676813 | 0.75 | ADAMTS7 (0.31) | ADAMTS7 | |
| Hydrochloric Acid SCHEMBL23354428 | 0.75 | ADAMTS7 (0.31) | ADAMTS7 | |
| SCHEMBL23354307 | 0.73 | ADAMTS7 (0.78) | ADAMTS7ADAMTS5ADAMTS4ADAM17MMP12 | |
| SCHEMBL29978929 | 0.73 | ADAMTS7 (0.78) | ADAMTS7ADAMTS5ADAMTS4ADAM17MMP12 | |
| SCHEMBL29873834 | 0.72 | ADAMTS7 (0.63) | ADAMTS7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027985-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027985-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | ADAMTS7, MMP7, ADAMTS1 | ADAMTS7 1/4885ADAMTS5 4/4885MMP2 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.