SCHEMBL24938708

SCHEMBL24938708

C1=CN(CCc2ccccc2)C=CC1=C1C=CN(CCc2ccccc2)C=C1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 2/20 0.48
GSK3B P49841 2/20 0.48
MGLL Q99685 2/20 0.48
SLC6A3 Q01959 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
CYP2A6 P11509 1/20 0.44
HTR2A P28223 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.44
SIGMAR1 Q99720 2/20 0.44
HRH3 Q9Y5N1 1/20 0.44
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 2/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CASP1 P29466 1/20 0.41
ALDH2 P05091 1/20 0.41
ALDH3A1 P30838 1/20 0.41
PARK7 Q99497 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24938710 0.77 MGLL (0.45) GSK3AGSK3BMGLLSMN1; SMN2CYP2A6
SCHEMBL28385174 0.77 SLC6A3 (0.44) GSK3AGSK3BMGLLSLC6A3SMN1; SMN2
Hydrochloric Acid SCHEMBL28835985 0.76 MGLL (0.43) GSK3AGSK3BMGLLSMN1; SMN2SIGMAR1
Hydrochloric Acid SCHEMBL30234811 0.74 MGLL (0.42) GSK3AGSK3BMGLLSMN1; SMN2SIGMAR1
Iodide SCHEMBL9160124 0.70 SLC6A3 (0.45) GSK3AGSK3BMGLLSLC6A3SMN1; SMN2
SCHEMBL1793454 0.69 ALDH1A1 (0.65) SMN1; SMN2CYP2A6HTR2ATAAR1LOXL2
Fluoride Ion SCHEMBL22320186 0.67 ALDH1A1 (0.61) SMN1; SMN2CYP2A6HTR2ATAAR1LOXL2
SCHEMBL2148794 0.67 SLC6A3 (0.47) GSK3AGSK3BMGLLSLC6A3SMN1; SMN2
SCHEMBL9741303 0.66 ALDH1A1 (0.69) SMN1; SMN2CYP2A6HTR2ATAAR1LOXL2
SCHEMBL62125 0.66 ALDH1A1 (0.69) SMN1; SMN2CYP2A6HTR2ATAAR1LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022263-A1 N-TYPE DOPANTS FOR PHOTOACTIVE REGIONS OF ORGANIC PHOTOVOLTAICS UNIV KING ABDULLAH SCI & TECH (SA) 2023-01-26 US disclosed