Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | BACE1 | P56817 | 7/20 | 0.44 |
| ▸ | CTSD | P07339 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19523060 | 0.81 | BCHE (0.49) | BCHEBACE1CTSDLMNACYP3A4 | |
| SCHEMBL12956598 | 0.81 | BCHE (0.56) | BCHEBACE1CTSDLMNAKMT2A | |
| SCHEMBL23366074 | 0.80 | BCHE (0.46) | BCHEBACE1CTSDLMNA | |
| SCHEMBL18626557 | 0.79 | BCHE (0.54) | BCHEBACE1CTSDLMNAKMT2A | |
| SCHEMBL10077679 | 0.78 | BACE1 (0.48) | BCHEBACE1CTSDCYP1A2KMT2A | |
| SCHEMBL5013630 | 0.77 | KDM4E (0.48) | BCHEBACE1CTSDCYP3A4ALOX15 | |
| SCHEMBL20115403 | 0.77 | HDAC4 (0.40) | BCHEBACE1CYP3A4ALOX15KDM4E | |
| SCHEMBL13999438 | 0.77 | BACE1 (0.50) | BCHEBACE1CTSDCLK1DYRK1A | |
| SCHEMBL18542697 | 0.77 | MC4R (0.54) | BCHEBACE1CTSDCYP1A2 | |
| SCHEMBL18232506 | 0.75 | BCHE (0.45) | BCHEBACE1CTSDLMNACLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560422-B2 | Sulfonamide-containing linkage systems for drug conjugates | ZYMEWORKS INC. | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560422-B2 | Sulfonamide-containing linkage systems for drug conjugates | MPST, TPST2, SULT1A1 | BCHE 2315/4885BACE1 3872/4885CTSD 3414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.