Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24939029 | 0.84 | CTRB1 (0.47) | CTRB1P2RX4P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL22184884 | 0.78 | HTR2C (0.55) | CTRB1P2RX4P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL9009580 | 0.77 | P2RX4 (0.50) | CTRB1P2RX4P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL274967 | 0.75 | P2RX4 (0.58) | CTRB1P2RX4P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL22175038 | 0.74 | HTR2C (0.50) | CTRB1P2RX4P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL8526862 | 0.73 | P2RX4 (0.55) | CTRB1P2RX4P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL20888347 | 0.73 | CTRB1 (0.46) | CTRB1P2RX4P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL22214513 | 0.73 | HTR2C (0.46) | CTRB1P2RX4P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL22175043 | 0.72 | HTR2C (0.48) | CTRB1P2RX4P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL29235094 | 0.70 | NPC1 (0.61) | CTRB1P2RX4P2RX1P2RX3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004409-A1 | GUIDE RNAS FOR CRISPR/CAS EDITING SYSTEMS | BEAM THERAPEUTICS INC. (US) | 2023-01-26 | — | — | WO | disclosed |