SCHEMBL274967

SCHEMBL274967

O=C1CCC(=O)N1C(=O)OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 2/20 0.58
CTRB1 P17538 1/20 0.57
P2RX1 P51575 1/20 0.56
P2RX3 P56373 1/20 0.56
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.51
ALDH1A1 P00352 3/20 0.50
HTR2C P28335 1/20 0.50
MAPK1 P28482 2/20 0.49
GAA P10253 1/20 0.49
CYP2C19 P33261 1/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
PSEN1 P49768 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8526862 0.93 P2RX4 (0.55) P2RX4CTRB1P2RX1P2RX3NPC1
SCHEMBL8777369 0.91 P2RX4 (0.50) P2RX4CTRB1P2RX1P2RX3NPC1
SCHEMBL12474901 0.87 NPC1 (0.63) P2RX4CTRB1P2RX1P2RX3NPC1
SCHEMBL11404740 0.84 HTR1A (0.47) P2RX4CTRB1P2RX1P2RX3NPC1
SCHEMBL6343082 0.83 ALDH1A1 (0.43) P2RX4CTRB1P2RX1P2RX3NPC1
SCHEMBL22184884 0.83 HTR2C (0.55) P2RX4CTRB1P2RX1P2RX3NPC1
SCHEMBL876243 0.81 SMN1; SMN2 (0.49) P2RX4CTRB1P2RX1P2RX3NPC1
SCHEMBL29235094 0.81 NPC1 (0.61) P2RX4CTRB1P2RX1P2RX3NPC1
SCHEMBL19984711 0.81 P2RX4 (0.64) P2RX4CTRB1P2RX1P2RX3NPC1
SCHEMBL2539997 0.80 NPC1 (0.67) P2RX4CTRB1P2RX1P2RX3NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 489 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119564933-A Preparation method of biological tissue material, prepared biological tissue material and application 上海易桥医疗器械有限公司 2025-03-07 CN claimed
US-20240150390-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-05-09 US claimed
WO-2024024935-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE HAVING ANTINEOPLASTIC EFFECT 第一三共株式会社 2024-02-01 WO claimed
EP-4286393-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE Daiichi Sankyo Company, Limited (JP) 2023-12-06 EP claimed
CN-116867795-A Novel method for producing antibody-immunostimulant conjugate 第一三共株式会社 2023-10-10 CN claimed
CN-116410145-A Preparation method of MRTX849 intermediate 上海泓博智源医药股份有限公司 2023-07-11 CN claimed
CN-112898204-B Synthesis method of N-carbobenzoxy-L-histidine 苏州昊帆生物股份有限公司 2023-05-12 CN claimed
WO-2022163846-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE 第一三共株式会社 2022-08-04 WO claimed
CN-112898204-A Synthesis method of N-benzyloxycarbonyl-L-histidine 苏州昊帆生物股份有限公司 2021-06-04 CN claimed
CN-110698381-A Method for synthesizing N- (benzyloxycarbonyl) succinimide by one-pot two-phase method 常州吉恩药业有限公司 2020-01-17 CN claimed
EP-0406734-A2 2-(Aminoaryl)indoles and indolines, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1991-01-09 EP claimed
US-20260116857-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOFS PARDES BIOSCIENCES INC (US) 2026-04-30 US disclosed
EP-3810615-B1 ARGINASE INHIBITORS AND METHODS OF USE MERCK SHARP & DOHME LLC (US) 2026-01-28 EP disclosed
EP-4656626-A1 COMPOUND AND METHOD FOR USING SAME, PLASTICIZER COMPOSITION, RESIN COMPOSITION, RESIN MOLDED BODY, AND LAMINATED BODY Zeon Corporation (JP) 2025-12-03 EP disclosed
EP-4615581-A2 FUSED MULTICYCLIC COMPOUNDS AND THEIR USE AS PARP1 INHIBITORS Laekna Pharmaceutical Ningbo Co., Ltd. (CN) 2025-09-17 EP disclosed
US-4331804-A ANTIBIOTICS ABBOTT LABORATORIES (US) 1982-05-25 US disclosed
US-4196197-A 2'N-Acyl and alkyl-6'-N-alkyl- and 6',6'-di-N-alkyl derivatives of fortimicins A and B ABBOTT LABORATORIES (US) 1980-04-01 US disclosed
US-4187297-A 3-De-O-methyl-2-N-acyl and alkyl fortimicins A and B ABBOTT LABORATORIES (US) 1980-02-05 US disclosed
US-4183920-A ANTIBIOTICS ABBOTT LABORATORIES (US) 1980-01-15 US disclosed
US-4166114-A AMINOGLYCOSIDE ANTIBIOTIC DERIVATIVES AND METHOD OF USE SHIONOGI & CO., LTD. (JP) 1979-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150390-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE PAICS, COASY, CDS2 P2RX4 1259/4885CTRB1 2556/4885P2RX1 1548/4885
US-20260116857-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOFS CTRC, CTRL, CTSL P2RX4 4483/4885CTRB1 28/4885P2RX1 4421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.