SCHEMBL2493944

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2493260	0.92	SCN9A (0.50)	SCN9ASCN10AGRM5CYP2C9
	SCHEMBL2495876	0.91	LMNA (0.48)	SCN9AGRM5LMNAMAPK1HTT
	SCHEMBL2498099	0.88	SCN9A (0.52)	SCN9ASCN10AGRM5CYP2C9
	SCHEMBL2498110	0.86	SCN9A (0.52)	SCN9ASCN10AGRM5CYP2C9
	SCHEMBL2498690	0.86	SCN9A (0.53)	SCN9ASCN10AGRM5CYP2C9
	SCHEMBL2497146	0.84	ADORA2A (0.46)	SCN9ALMNAMAPK1HTTTDP1
	SCHEMBL2498135	0.84	POLB (0.47)	LMNATUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL2500983	0.83	SCN9A (0.54)	SCN9ASCN10AGRM5CYP2C9
	SCHEMBL1883650	0.83	SCN9A (0.58)	SCN9ASCN10AGRM5CYP2C9
	SCHEMBL2501402	0.83	USP30 (0.45)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.