SCHEMBL24939780

SCHEMBL24939780

CC1=CC(=O)N(c2ccc(C(=O)O)c(C(F)(F)F)c2)C1=O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 3/20 0.44
ALKBH5 Q6P6C2 2/20 0.41
PIM3 Q86V86 1/20 0.39
HIPK4 Q8NE63 1/20 0.39
SCN2A Q99250 1/20 0.39
TYMS P04818 1/20 0.38
AR P10275 2/20 0.38
XPO1 O14980 3/20 0.37
CFTR P13569 2/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24939862 0.85 PIM3 (0.41) NOTUMPIM3HIPK4SCN2ATYMS
SCHEMBL24938793 0.83 NPSR1 (0.46) PIM3HIPK4SCN2ATYMSPTGS1
SCHEMBL24939813 0.81 PIM3 (0.40) NOTUMPIM3HIPK4SCN2ATYMS
SCHEMBL24939847 0.81 MYC (0.56) NOTUMPIM3HIPK4SCN2ATYMS
SCHEMBL6499776 0.80 XPO1 (0.42) ARXPO1
SCHEMBL24939776 0.80 PTGS1 (0.51) NOTUMPIM3HIPK4SCN2APTGS1
SCHEMBL24939827 0.78 ALDH1A1 (0.47) PIM3HIPK4SCN2ATYMSPTGS1
SCHEMBL6659492 0.76 PTGS1 (0.55) PIM3HIPK4SCN2ATYMSPTGS1
SCHEMBL10793190 0.76 PTGS1 (0.51) PTGS1PTGS2
SCHEMBL24939784 0.74 PIM3 (0.43) NOTUMALKBH5PIM3HIPK4SCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS GFER, LBR, PCNA NOTUM 1742/4885ALKBH5 23/4885PIM3 1314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.