SCHEMBL24939776

SCHEMBL24939776

O=C(O)c1ccc(N2C(=O)C=CC2=O)cc1C(F)(F)F

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.51
PTGS2 P35354 1/20 0.51
DDAH1 O94760 1/20 0.50
NSD2 O96028 1/20 0.46
G6PD P11413 1/20 0.46
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
NPSR1 Q6W5P4 2/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45
HTT P42858 1/20 0.45
MGLL Q99685 5/20 0.44
FAAH O00519 3/20 0.44
NOTUM Q6P988 2/20 0.44
HSP90AA1 P07900 2/20 0.42
PKM P14618 1/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11563858 0.81 PTGS1 (0.62) PTGS1PTGS2DDAH1NSD2G6PD
SCHEMBL24938794 0.80 PTGS1 (0.54) PTGS1PTGS2DDAH1NSD2G6PD
SCHEMBL24939780 0.80 NOTUM (0.44) PTGS1PTGS2NOTUMPIM3HIPK4
SCHEMBL21846610 0.80 MGLL (0.50) NPSR1ALDH1A1LMNAMGLLFAAH
SCHEMBL28343010 0.78 PTGS1 (0.55) PTGS1PTGS2DDAH1NSD2G6PD
SCHEMBL29567433 0.78 PIM3 (0.64) PTGS1PTGS2DDAH1NSD2G6PD
SCHEMBL3050771 0.78 PIM3 (0.64) PTGS1PTGS2DDAH1NSD2G6PD
SCHEMBL24939784 0.78 PIM3 (0.43) NOTUMPIM3HIPK4SCN2A
SCHEMBL24938790 0.77 DDAH1 (0.58) PTGS1PTGS2DDAH1NSD2G6PD
SCHEMBL3198851 0.77 ALKBH5 (0.49) G6PDNPSR1MGLLFAAHNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS GFER, LBR, PCNA PTGS1 3908/4885PTGS2 3014/4885DDAH1 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.