SCHEMBL24939788

SCHEMBL24939788

O=C(O)c1cc(I)c(N2C(=O)C=CC2=O)c(I)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.58
G6PD P11413 1/20 0.58
KEAP1 Q14145 1/20 0.58
NFE2L2 Q16236 1/20 0.58
TPMT P51580 5/20 0.52
DDAH1 O94760 1/20 0.48
MGLL Q99685 4/20 0.37
PTGS1 P23219 2/20 0.37
PTGS2 P35354 2/20 0.37
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA7 P43166 2/20 0.35
CA9 Q16790 2/20 0.35
CA14 Q9ULX7 2/20 0.35
FAAH O00519 2/20 0.35
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
HSP90AA1 P07900 2/20 0.35
ATM Q13315 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24939698 0.78 TPMT (0.48) NSD2G6PDKEAP1NFE2L2TPMT
SCHEMBL24939791 0.77 NSD2 (0.41) NSD2G6PDKEAP1NFE2L2TPMT
SCHEMBL24939671 0.77 DDAH1 (0.53) NSD2G6PDKEAP1NFE2L2TPMT
SCHEMBL24939798 0.76 TPMT (0.43) NSD2G6PDKEAP1NFE2L2TPMT
SCHEMBL24939694 0.74 TPMT (0.44) NSD2G6PDKEAP1NFE2L2TPMT
SCHEMBL11416336 0.74 NSD2 (0.92) NSD2G6PDKEAP1NFE2L2DDAH1
SCHEMBL3469456 0.74 NSD2 (1.00) NSD2G6PDKEAP1NFE2L2DDAH1
Hydrochloric Acid SCHEMBL9622188 0.72 NSD2 (0.88) NSD2G6PDKEAP1NFE2L2DDAH1
SCHEMBL122324 0.69 TPMT (1.00) TPMTCA12CA1CA2CA7
Hydrochloric Acid SCHEMBL4265743 0.68 TPMT (0.95) TPMTCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS GFER, LBR, PCNA NSD2 435/4885G6PD 1659/4885KEAP1 3844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.