SCHEMBL24939671

SCHEMBL24939671

O=C(O)c1ccc(N2C(=O)C=CC2=O)c(I)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 1/20 0.53
MGLL Q99685 1/20 0.50
NSD2 O96028 1/20 0.49
G6PD P11413 1/20 0.49
KEAP1 Q14145 1/20 0.49
NFE2L2 Q16236 1/20 0.49
TLR9 Q9NR96 3/20 0.43
ALDH1A1 P00352 2/20 0.43
HSP90AA1 P07900 2/20 0.43
ATM Q13315 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
MITF O75030 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
PKM P14618 1/20 0.42
CCR6 P51684 1/20 0.42
TPMT P51580 2/20 0.42
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
MYC P01106 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17301073 0.84 DDAH1 (0.58) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL24939849 0.83 TSHR (0.53) DDAH1MGLLNSD2G6PDKEAP1
SCHEMBL24939676 0.81 MYC (0.56) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL24939670 0.80 MYC (0.45) ALDH1A1HSP90AA1NPSR1TDP1TPMT
Hydrochloric Acid SCHEMBL11453925 0.79 DDAH1 (0.53) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL24938792 0.79 MYC (0.60) DDAH1MGLLNSD2G6PDKEAP1
SCHEMBL24939672 0.79 MYC (0.41) ALDH1A1NPSR1TDP1TPMTMYC
SCHEMBL24939788 0.77 NSD2 (0.58) DDAH1MGLLNSD2G6PDKEAP1
SCHEMBL24939669 0.76 POLB (0.45) ALDH1A1TDP1TPMTHSD17B10GAA
SCHEMBL20945174 0.76 ALDH1A1 (0.58) DDAH1MGLLNSD2G6PDKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS GFER, LBR, PCNA DDAH1 93/4885MGLL 2091/4885NSD2 435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.