SCHEMBL122324

SCHEMBL122324

O=C(O)c1cc(I)c(I)c(I)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TPMT P51580 5/20 1.00
▸ CA12 O43570 3/20 0.48
▸ CA1 P00915 3/20 0.48
▸ CA2 P00918 3/20 0.48
▸ CA7 P43166 3/20 0.48
▸ CA9 Q16790 3/20 0.48
▸ CA14 Q9ULX7 3/20 0.48
▸ TP53 P04637 2/20 0.46
▸ CA3 P07451 2/20 0.46
▸ CA4 P22748 2/20 0.46
▸ CA6 P23280 2/20 0.46
▸ CA5A P35218 2/20 0.46
▸ CA5B Q9Y2D0 2/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ SELL P14151 1/20 0.46
▸ HPGD P15428 1/20 0.46
▸ SELP P16109 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4265743 0.97 TPMT (0.95) TPMTCA12CA1CA2CA7
SCHEMBL23817375 0.84 TPMT (0.71) TPMTCA12CA1CA2CA7
SCHEMBL14275457 0.82 TPMT (0.67) TPMTMAPTMAPK1TDP1TSHR
SCHEMBL1613916 0.81 TPMT (0.68) TPMTCA12CA1CA2CA7
SCHEMBL16049973 0.79 TPMT (0.65) TPMTCA12CA1CA2CA7
SCHEMBL864680 0.79 TPMT (0.65) TPMTCA12CA1CA2CA7
SCHEMBL21836922 0.79 TPMT (0.65) TPMTCA12CA1CA2CA7
SCHEMBL25610863 0.79 TPMT (0.65) TPMTCA12CA1CA2CA7
SCHEMBL670788 0.76 TTR (0.65) TPMTCA12CA1CA2CA7
SCHEMBL14264012 0.76 TPMT (0.61) TPMTCA5ALMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116875024-A Hydrogel with X-ray visibility and preparation method and application thereof 赛克赛斯生物科技股份有限公司 2023-10-13 — — CN claimed
EP-3631442-A1 FUNCTIONLIZED CALIBRANTS FOR SPECTROMETRY AND CHROMATOGRAPHY The Administrators of The Tulane Educational Fund (US) 2020-04-08 — — EP claimed
WO-2018222593-A1 FUNCTIONLIZED CALIBRANTS FOR SPECTROMETRY AND CHROMATOGRAPHY THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2018-12-06 — — WO claimed
EP-2066362-A1 RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF Boston Scientific Limited (BB) 2009-06-10 — — EP claimed
WO-2008033198-A1 RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF BOSTON SCIENTIFIC LIMITED (BB) 2008-03-20 — — WO claimed
US-20080064848-A1 Radiopaque amide polymers and medical devices formed thereof BOSTON SCIENTIFIC SCIMED, INC. (US) 2008-03-13 — — US claimed
EP-0070198-B1 RADIATION-SENSITIVE COMPOSITION AND PATTERN-FORMATION METHOD USING THE SAME Hitachi, Ltd. (JP) 1985-06-19 — — EP claimed
EP-0070198-A1 Radiation-sensitive composition and pattern-formation method using the same Hitachi, Ltd. (JP) 1983-01-19 — — EP claimed
EP-0050457-A1 Radiopaque cyanoacrylate compositions BioNexus, Inc. (US) 1982-04-28 — — EP claimed
CN-122028942-A Gel for treating fistulae and related methods 波士顿科学国际有限公司 2026-05-12 — — CN disclosed
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 — — US disclosed
US-20260049178-A1 CROSSLINKING AGENTS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-02-19 — — US disclosed
US-20260041799-A1 HYDROLYSIS-RESISTANT HYDROGELS AND METHODS OF TREATMENT USING SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-02-12 — — US disclosed
US-20260014282-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES FOR USE IN MEDICAL HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-01-15 — — US disclosed
WO-1990009450-A2 METHOD FOR INCREASING THE ABILITY OF MAIZE TO UNDERGO ANDROGENESIS, AND PRODUCTS PRODUCED THEREFROM UNITED AGRISEEDS, INC. (US) 1990-08-23 — — WO disclosed
EP-0111608-B1 PSEUDOTROPYL HALOGENO-BENZOATES AND THEIR USE IN MIGRAINE TREATMENT MERRELL TORAUDE ET COMPAGNIE (FR) 1987-03-11 — — EP disclosed
EP-0070198-B1 RADIATION-SENSITIVE COMPOSITION AND PATTERN-FORMATION METHOD USING THE SAME Hitachi, Ltd. (JP) 1985-06-19 — — EP disclosed
US-4486441-A PROPHYLAXIS MERRELL TORAUDE ET COMPAGNIE (FR) 1984-12-04 — — US disclosed
US-4465768-A Pattern-formation method with iodine containing azide and oxygen plasma etching of substrate HITACHI, LTD. (JP) 1984-08-14 — — US disclosed
EP-0111608-A1 Pseudotropyl halogeno-benzoates and their use in migraine treatment MERRELL TORAUDE ET COMPAGNIE (FR) 1984-06-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS KLK3, BRDT, BPHL TPMT 4080/4885CA12 233/4885CA1 390/4885
US-20260049178-A1 CROSSLINKING AGENTS AND MEDICAL HYDROGELS FORMED THEREFROM NPPA, MACF1, IGF1R TPMT 3130/4885CA12 232/4885CA1 1009/4885
US-20260014282-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES FOR USE IN MEDICAL HYDROGELS IAPP, NPPA, ARG1 TPMT 4779/4885CA12 347/4885CA1 226/4885
US-20260041799-A1 HYDROLYSIS-RESISTANT HYDROGELS AND METHODS OF TREATMENT USING SAME PAM, CRYAA, COL1A1 TPMT 3261/4885CA12 1211/4885CA1 844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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