SCHEMBL24939840

SCHEMBL24939840

CC1=C(C)C(=O)N(c2ccc(C(=O)O)c(O)c2)C1=O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM3 Q86V86 1/20 0.69
HIPK4 Q8NE63 1/20 0.69
SCN2A Q99250 1/20 0.69
TYMS P04818 1/20 0.64
MYC P01106 2/20 0.61
DUSP3 P51452 2/20 0.61
KLKB1 P03952 1/20 0.61
CTSB P07858 1/20 0.61
ELANE P08246 1/20 0.61
MMP9 P14780 1/20 0.61
ALDH1A1 P00352 4/20 0.54
KDM4E B2RXH2 3/20 0.54
POLB P06746 2/20 0.54
HPGD P15428 2/20 0.54
MAPK1 P28482 1/20 0.54
HSD17B10 Q99714 1/20 0.54
TSHR P16473 2/20 0.52
DUSP22 Q9NRW4 1/20 0.49
MEN1 O00255 1/20 0.49
PKM P14618 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9308287 0.87 PKM (0.61) PIM3HIPK4SCN2ATYMSMYC
SCHEMBL10932335 0.86 PIM3 (0.51) PIM3HIPK4SCN2ATYMSMYC
SCHEMBL24938795 0.85 NPSR1 (0.54) PIM3HIPK4SCN2ATYMSMYC
SCHEMBL10065488 0.83 PIM3 (0.49) PIM3HIPK4SCN2ATYMSMYC
SCHEMBL24939851 0.82 MYC (0.62) PIM3HIPK4SCN2ATYMSMYC
SCHEMBL24939814 0.82 PIM3 (0.48) PIM3HIPK4SCN2ATYMSMYC
SCHEMBL21889940 0.82 PIM3 (0.77) PIM3HIPK4SCN2ATYMSMYC
SCHEMBL38651889 0.82 SCN2A (1.00) PIM3HIPK4SCN2ATYMSMYC
SCHEMBL15437751 0.80 PIM3 (0.73) PIM3HIPK4SCN2ATYMSMYC
SCHEMBL24939830 0.80 PIM3 (0.64) PIM3HIPK4SCN2ATYMSMYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS GFER, LBR, PCNA PIM3 1314/4885HIPK4 519/4885SCN2A 958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.