Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.53 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.53 |
| ▸ | MYC | P01106 | 3/20 | 0.50 |
| ▸ | TYMS | P04818 | 1/20 | 0.50 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24939840 | 0.87 | PIM3 (0.69) | PKMPIM3HIPK4SCN2AMYC | |
| SCHEMBL10932335 | 0.86 | PIM3 (0.51) | PKMPIM3HIPK4SCN2AMYC | |
| SCHEMBL24938795 | 0.81 | NPSR1 (0.54) | PKMPIM3HIPK4SCN2AMYC | |
| SCHEMBL10065488 | 0.80 | PIM3 (0.49) | PKMPIM3HIPK4SCN2AMYC | |
| SCHEMBL9309327 | 0.80 | PIM3 (0.49) | PKMCSNK2A1PIM3HIPK4SCN2A | |
| SCHEMBL15437835 | 0.80 | PIM3 (0.56) | PKMPIM3HIPK4SCN2AMYC | |
| SCHEMBL11668068 | 0.79 | PTGS2 (0.59) | PKMCSNK2A1PIM3HIPK4SCN2A | |
| SCHEMBL24939814 | 0.79 | PIM3 (0.48) | PKMPIM3HIPK4SCN2AMYC | |
| SCHEMBL24939851 | 0.79 | MYC (0.62) | PKMPIM3HIPK4SCN2AMYC | |
| SCHEMBL24939828 | 0.76 | ALDH1A1 (0.51) | PIM3HIPK4SCN2AMYCTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288694-A | Herbicides | BAYER ATKIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |
| EP-0545167-A1 | N-(4-hydroxyphenyl)-maleimides and N-(4-hydroxyphenyl)-tetrahydro-phthalimides and their use as herbicides | BAYER AG (DE) | 1993-06-09 | — | — | EP | disclosed |