SCHEMBL24938795

SCHEMBL24938795

CC1=C(C)C(=O)N(c2ccc(C(=O)O)c(C)c2)C1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.54
TYMS P04818 2/20 0.51
SCN2A Q99250 2/20 0.50
PIM3 Q86V86 1/20 0.50
HIPK4 Q8NE63 1/20 0.50
PARP1 P09874 1/20 0.49
PARP15 Q460N3 1/20 0.49
PARP10 Q53GL7 1/20 0.49
MYC P01106 3/20 0.46
CTSB P07858 2/20 0.46
KLKB1 P03952 1/20 0.46
ELANE P08246 1/20 0.46
MMP9 P14780 1/20 0.46
DUSP3 P51452 1/20 0.46
CA12 O43570 3/20 0.45
CA1 P00915 3/20 0.45
CA9 Q16790 3/20 0.45
NR4A1 P22736 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10932335 0.88 PIM3 (0.51) NPSR1TYMSSCN2APIM3HIPK4
SCHEMBL10065488 0.85 PIM3 (0.49) NPSR1TYMSSCN2APIM3HIPK4
SCHEMBL24939840 0.85 PIM3 (0.69) TYMSSCN2APIM3HIPK4PARP1
SCHEMBL24939851 0.83 MYC (0.62) NPSR1TYMSSCN2APIM3HIPK4
SCHEMBL24939814 0.83 PIM3 (0.48) NPSR1TYMSSCN2APIM3HIPK4
SCHEMBL24938791 0.83 TYMS (0.49) NPSR1TYMSSCN2APIM3HIPK4
SCHEMBL24938790 0.83 DDAH1 (0.58) NPSR1TYMSSCN2APIM3HIPK4
SCHEMBL9308287 0.81 PKM (0.61) TYMSSCN2APIM3HIPK4PARP1
SCHEMBL24939828 0.81 ALDH1A1 (0.51) TYMSSCN2APIM3HIPK4PARP1
SCHEMBL24938793 0.81 NPSR1 (0.46) NPSR1TYMSSCN2APIM3HIPK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS GFER, LBR, PCNA NPSR1 3288/4885TYMS 2599/4885SCN2A 958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.