Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 14/20 | 0.80 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.73 |
| ▸ | TK1 | P04183 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | POLA1 | P09884 | 1/20 | 0.63 |
| ▸ | POLG | P54098 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053832 | 0.87 | HPRT1 (0.74) | PNPHPRT1POLBPOLA1POLG | |
| SCHEMBL13619242 | 0.86 | PNP (0.79) | PNPHPRT1POLBPOLG | |
| SCHEMBL11308931 | 0.84 | PNP (0.88) | PNPHPRT1POLBPOLA1POLG | |
| SCHEMBL9515948 | 0.84 | PNP (1.00) | PNPHPRT1TK1 | |
| SCHEMBL11327665 | 0.83 | PNP (0.86) | PNPHPRT1POLBPOLA1POLG | |
| SCHEMBL11313321 | 0.83 | PNP (0.86) | PNPHPRT1POLBPOLA1POLG | |
| Ammonia Solution, Strong SCHEMBL11310327 | 0.83 | PNP (0.86) | PNPHPRT1POLBPOLA1POLG | |
| SCHEMBL8905164 | 0.83 | HPRT1 (0.72) | PNPHPRT1POLBPOLA1POLG | |
| SCHEMBL8905172 | 0.82 | HPRT1 (0.71) | PNPHPRT1POLBPOLA1POLG | |
| SCHEMBL8172148 | 0.82 | TK1 (0.69) | PNPHPRT1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007019-A9 | CAP ANALOGS HAVING AN ACYCLIC LINKER TO THE GUANINE DERIVATIVE NUCLEOBASE | CureVac SE (DE) | 2024-02-29 | — | — | WO | disclosed |
| WO-2023007019-A1 | CAP ANALOGS HAVING AN ACYCLIC LINKER TO THE GUANINE DERIVATIVE NUCLEOBASE | CureVac SE (DE) | 2023-02-02 | — | — | WO | disclosed |