Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.59 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.59 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.59 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22302225 | 0.89 | GNAI3 (0.67) | GNAI3GNAO1GNAI1NAAASMN1; SMN2 | |
| SCHEMBL26143587 | 0.83 | GNAI3 (0.55) | GNAI3GNAO1GNAI1NAAASMN1; SMN2 | |
| SCHEMBL22301809 | 0.83 | CYP3A4 (0.64) | GNAI3GNAO1GNAI1NAAATSHR | |
| SCHEMBL24865973 | 0.83 | TSHR (0.64) | GNAI3GNAO1GNAI1NAAATSHR | |
| SCHEMBL17285633 | 0.81 | GNAI3 (0.55) | GNAI3GNAO1GNAI1NAAASMN1; SMN2 | |
| SCHEMBL19009042 | 0.81 | SMN1; SMN2 (0.63) | GNAI3GNAO1GNAI1SMN1; SMN2KDM4E | |
| SCHEMBL26143580 | 0.80 | ALDH1A1 (0.61) | GNAI3GNAO1GNAI1NAAATSHR | |
| SCHEMBL26203010 | 0.79 | HSD17B10 (0.55) | GNAI3GNAO1GNAI1NAAASMN1; SMN2 | |
| SCHEMBL10108953 | 0.78 | SMN1; SMN2 (0.51) | GNAI3GNAO1GNAI1SMN1; SMN2TSHR | |
| SCHEMBL24941806 | 0.77 | GNAI3 (0.49) | GNAI3GNAO1GNAI1NAAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560381-B1 | Compounds and uses thereof | FOGHORN THERAPEUTICS INC. (US) | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560381-B1 | Compounds and uses thereof | VHL, TFEB, BECN1 | GNAI3 1978/4885GNAO1 3003/4885GNAI1 1812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.