Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25089968 | 0.91 | NAMPT (0.35) | NAMPTHRH3BCHEACHE | |
| SCHEMBL26330301 | 0.83 | NAMPT (0.48) | NAMPT | |
| SCHEMBL26143702 | 0.83 | NAMPT (0.35) | NAMPTHRH3HTR4HTR1AHTR7 | |
| SCHEMBL25089653 | 0.81 | NAMPT (0.35) | NAMPT | |
| SCHEMBL22302241 | 0.79 | DRD2 (0.34) | HRH3BCHEACHEHTR4 | |
| SCHEMBL25090025 | 0.77 | HTR4 (0.31) | BCHEACHEHTR4 | |
| SCHEMBL25101406 | 0.77 | HTR4 (0.33) | HRH3BCHEACHEHTR4 | |
| SCHEMBL25089996 | 0.76 | NAMPT (0.35) | NAMPTHRH3 | |
| SCHEMBL25101607 | 0.75 | NAMPT (0.35) | NAMPTHRH3 | |
| SCHEMBL25090028 | 0.74 | HTR4 (0.33) | HRH3BCHEACHEHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142883-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-11 | — | — | US | disclosed |
| US-11560381-B1 | Compounds and uses thereof | FOGHORN THERAPEUTICS INC. (US) | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142883-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | NAMPT 1153/4885HRH3 2014/4885BCHE 3724/4885 |
| US-11560381-B1 | Compounds and uses thereof | VHL, TFEB, BECN1 | NAMPT 1153/4885HRH3 2014/4885BCHE 3724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.