Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24185572 | 0.88 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1ALOX15KDM1ALMNA | |
| SCHEMBL24327671 | 0.83 | LMNA (0.32) | LMNACYP2C9 | |
| SCHEMBL22565449 | 0.81 | LMNA (0.42) | ALDH1A1KDM1ALMNACYP2C9NCF1 | |
| SCHEMBL26778326 | 0.79 | LMNA (0.30) | LMNACYP2C9 | |
| SCHEMBL17001880 | 0.79 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1ALOX15KDM1ALMNA | |
| SCHEMBL24185136 | 0.79 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1ALOX15KDM1AL3MBTL3 | |
| SCHEMBL27046813 | 0.78 | LMNA (0.33) | LMNACYP2C9 | |
| SCHEMBL21949557 | 0.77 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1ALOX15KDM1AL3MBTL3 | |
| SCHEMBL25001498 | 0.77 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1ALOX15KDM1AL3MBTL3 | |
| SCHEMBL26004078 | 0.77 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1ALOX15KDM1AL3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006088-A1 | COMPOUND FOR EGFR KINASE INHIBITOR, COMPOSITION AND USE THEREOF | 浙江大学智能创新药物研究院 | 2023-02-02 | — | — | WO | disclosed |