SCHEMBL24327671

SCHEMBL24327671

CN1C2CC1CN(C1CCN(I)CC1)C2

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24940937 0.83 ALDH1A1 (0.42) LMNACYP2C9
SCHEMBL24327676 0.79
SCHEMBL24327684 0.79
SCHEMBL24327678 0.79
SCHEMBL26778326 0.76 LMNA (0.30) LMNACYP2C9
SCHEMBL26805547 0.76 KDM4E (0.30)
SCHEMBL20069488 0.74
SCHEMBL25955648 0.72 ALDH1A1 (0.33)
SCHEMBL18636756 0.71 L3MBTL1 (0.38)
SCHEMBL19334369 0.71 LMNA (0.36) LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022063106-A1 INDOLINE COMPOUNDS AND DERIVATIVES AS EGFR INHIBITORS BEIGENE, LTD. (KY) 2022-03-31 WO disclosed