SCHEMBL2494552

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL992027	0.97	KIF11 (0.42)	KIF11NR3C2LMNAHTTCA1
	SCHEMBL2491447	0.91	KIF11 (0.40)	KIF11NR3C2LMNAHTTCA1
	SCHEMBL2491593	0.90	CA1 (0.41)	LMNACA1CA2CA12CA4
	SCHEMBL18704105	0.88	KIF11 (0.38)	KIF11NR3C2LMNAHTTALDH1A1
	SCHEMBL1260567	0.85	ALDH1A1 (0.42)	KIF11NR3C2LMNAHTTALDH1A1
	SCHEMBL15841458	0.85	ALDH1A1 (0.42)	KIF11NR3C2LMNAHTTALDH1A1
	SCHEMBL2489422	0.84	KIF11 (0.64)	KIF11NR3C2CA1CA2CA12
	SCHEMBL9215761	0.84	KIF11 (0.42)	KIF11NR3C2LMNAHTTCA1
	Tetraethylene Glycol SCHEMBL2385287	0.84	ALDH1A1 (0.39)	NR3C2LMNAHTTCA1CA2
	SCHEMBL2491452	0.82	KIF11 (0.51)	KIF11NR3C2ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.