SCHEMBL2491593

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL992027	0.90	KIF11 (0.42)	CA1CA2CA12CA4CA7
	SCHEMBL2494552	0.90	KIF11 (0.42)	CA1CA2CA12CA4CA7
	SCHEMBL2494964	0.90	ALDH1A1 (0.41)	CA1CA2CA12CA4CA7
	SCHEMBL2490799	0.82	KIF11 (0.52)	CA1CA2CA12CA4CA7
	SCHEMBL18704105	0.82	KIF11 (0.38)	ALDH1A1HSD17B10L3MBTL1CTNNB1WNT3A
	SCHEMBL2491447	0.81	KIF11 (0.40)	CA1CA2CA12CA4CA7
	SCHEMBL2493848	0.79	TAAR1 (0.43)	CA1CA2CA12CA4CA7
	SCHEMBL15841458	0.79	ALDH1A1 (0.42)	ALDH1A1HSD17B10L3MBTL1LMNAKDM4E
	SCHEMBL1260567	0.79	ALDH1A1 (0.42)	ALDH1A1HSD17B10L3MBTL1LMNAKDM4E
	SCHEMBL2490811	0.78	ALDH1A1 (0.36)	ALDH1A1TSHRL3MBTL1GAACTNNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.