SCHEMBL24945942

SCHEMBL24945942

CC(OC(=O)C(O)(C(F)(F)F)C(F)(F)F)c1ccc(F)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.36
KDM5A P29375 1/20 0.36
KDM4C Q9H3R0 1/20 0.36
KDM5B Q9UGL1 1/20 0.36
HTT P42858 2/20 0.36
ADRB2 P07550 2/20 0.35
ADRB1 P08588 2/20 0.35
ADRB3 P13945 2/20 0.35
LMNA P02545 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24177827 0.85 HCAR2 (0.49) HTTLMNANPSR1HCAR2KMT2A
SCHEMBL4622052 0.85 HTT (0.38) KDM5AKDM4CKDM5BHTTHDAC3
SCHEMBL22864017 0.82 PTGS2 (0.35) HTTLMNANPSR1HCAR2KMT2A
SCHEMBL25574955 0.81 ELANE (0.42) KDM5AKDM4CKDM5BHTTLMNA
SCHEMBL24901136 0.81 HTR2A (0.36) ADRB2ADRB1ADRB3LMNAHDAC3
SCHEMBL24901126 0.80 KCNK3 (0.31)
SCHEMBL22201767 0.75 HDAC3 (0.41) HTTHDAC3HDAC4HDAC1HDAC7
SCHEMBL13876380 0.75 HDAC3 (0.41) HTTHDAC3HDAC4HDAC1HDAC7
SCHEMBL28649908 0.74 ALDH1A1 (0.41) HTTHDAC3HDAC4HDAC1HDAC7
SCHEMBL9090928 0.74 ALDH1A1 (0.41) HTTHDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS HNRNPU, EWSR1, HNRNPR HSD11B1 3817/4885KDM5A 4188/4885KDM4C 3901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.