SCHEMBL24945943

SCHEMBL24945943

O=C(OC(c1ccccc1)C(F)(F)F)C(O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.39
NPSR1 Q6W5P4 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
GAA P10253 1/20 0.39
MAPK1 P28482 2/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
PDPK1 O15530 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
TACR1 P25103 1/20 0.35
CYP2D6 P10635 1/20 0.34
SRC P12931 1/20 0.34
ACP1 P24666 1/20 0.34
PTPN7 P35236 1/20 0.34
PTPN12 Q05209 1/20 0.34
PTPN13 Q12923 1/20 0.34
SSU72 Q9NP77 1/20 0.34
TACR3 P29371 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24901136 0.85 HTR2A (0.36) MAPK1KMT2ALMNA
SCHEMBL27801809 0.80 POLB (0.41) POLBNPSR1L3MBTL1GAAMAPK1
SCHEMBL24177827 0.80 HCAR2 (0.49) POLBNPSR1KMT2AMEN1PDPK1
SCHEMBL5932732 0.79 POLB (0.40) POLBNPSR1L3MBTL1GAAMAPK1
SCHEMBL11223311 0.77 CYP2D6 (0.42) POLBNPSR1L3MBTL1GAAMAPK1
SCHEMBL5933483 0.77 POLB (0.39) POLBNPSR1L3MBTL1GAAMAPK1
SCHEMBL28852545 0.77 NPSR1 (0.44) POLBNPSR1L3MBTL1GAAMAPK1
SCHEMBL9800763 0.77 POLB (0.39) POLBNPSR1L3MBTL1GAAMAPK1
SCHEMBL14269935 0.76 RIPK1 (0.38) NPSR1L3MBTL1GAAMAPK1KMT2A
SCHEMBL4730584 0.75 ESR1 (0.40) POLBNPSR1L3MBTL1GAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS HNRNPU, EWSR1, HNRNPR POLB 31/4885NPSR1 715/4885L3MBTL1 2700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.