Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27801809 | 0.85 | POLB (0.41) | CYP2D6KMT2APOLBNPSR1L3MBTL1 | |
| SCHEMBL5932732 | 0.83 | POLB (0.40) | CYP2D6KMT2APOLBNPSR1L3MBTL1 | |
| SCHEMBL9800752 | 0.83 | POLB (0.35) | CYP2D6KMT2APOLBNPSR1L3MBTL1 | |
| SCHEMBL28852545 | 0.81 | NPSR1 (0.44) | CYP2D6KMT2APOLBNPSR1L3MBTL1 | |
| SCHEMBL5933483 | 0.81 | POLB (0.39) | CYP2D6KMT2APOLBNPSR1L3MBTL1 | |
| SCHEMBL8737348 | 0.81 | ALDH1A1 (0.40) | KMT2APOLBNPSR1L3MBTL1GAA | |
| SCHEMBL4730584 | 0.79 | ESR1 (0.40) | CYP2D6KMT2APOLBNPSR1L3MBTL1 | |
| SCHEMBL3420270 | 0.79 | ALDH1A1 (0.40) | KMT2APOLBNPSR1L3MBTL1GAA | |
| SCHEMBL24945943 | 0.77 | POLB (0.39) | CYP2D6KMT2APOLBNPSR1L3MBTL1 | |
| SCHEMBL5088009 | 0.77 | THRB (0.38) | CYP2D6KMT2APOLBNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358606-A | Esters of phenalkyloxycarbonylamino acids | ZOECON CORPORATION (US) | 1982-11-09 | — | — | US | disclosed |