Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15540502 | 0.77 | CTSK (0.31) | USP2SMN1; SMN2NR1H2 | |
| SCHEMBL1163659 | 0.77 | CTSK (0.31) | USP2SMN1; SMN2NR1H2 | |
| SCHEMBL2494815 | 0.76 | PREP (0.39) | GPR119PREPBUB1USP2SMN1; SMN2 | |
| SCHEMBL1565496 | 0.73 | BUB1 (0.36) | GPR119PREPBUB1USP2SMN1; SMN2 | |
| SCHEMBL28423661 | 0.71 | BUB1 (0.36) | GPR119BUB1USP2SMN1; SMN2NR1H2 | |
| SCHEMBL6188259 | 0.70 | USP2 (0.38) | GPR119PREPBUB1USP2SMN1; SMN2 | |
| SCHEMBL15405772 | 0.70 | USP2 (0.38) | GPR119PREPBUB1USP2SMN1; SMN2 | |
| SCHEMBL28831848 | 0.70 | USP2 (0.38) | GPR119PREPBUB1USP2SMN1; SMN2 | |
| SCHEMBL16594444 | 0.70 | USP2 (0.38) | GPR119PREPBUB1USP2SMN1; SMN2 | |
| SCHEMBL28150229 | 0.70 | NR1H2 (0.33) | USP2SMN1; SMN2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030499-B2 | 1,3-dihydro-2H-indole-2-one compound and pyrrolidine-2-one compound fused with aromatic heterocycle | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-10-04 | — | — | US | disclosed |