Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28150232 | 0.89 | NR1H2 (0.31) | NR1H2ABCB1FAAH | |
| SCHEMBL28490304 | 0.87 | NR1H2 (0.30) | NR1H2ABCB1 | |
| SCHEMBL28149261 | 0.76 | FAAH (0.31) | FAAHCTSK | |
| SCHEMBL28149262 | 0.72 | FAAH (0.31) | FAAH | |
| SCHEMBL28149263 | 0.70 | — | — | |
| SCHEMBL2494601 | 0.70 | GPR119 (0.34) | NR1H2USP2SMN1; SMN2 | |
| SCHEMBL1163659 | 0.70 | CTSK (0.31) | NR1H2ABCB1CTSKUSP2SMN1; SMN2 | |
| SCHEMBL15540502 | 0.70 | CTSK (0.31) | NR1H2ABCB1CTSKUSP2SMN1; SMN2 | |
| SCHEMBL28499390 | 0.69 | CTSK (0.36) | NR1H2FAAHCTSKUSP2SMN1; SMN2 | |
| SCHEMBL28273267 | 0.64 | USP2 (0.40) | NR1H2ABCB1CTSKUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106883238-B | Preparation method of alpha-azaspiro compound | 贵州医科大学 | 2020-12-18 | — | — | CN | disclosed |
| CN-106883238-A | A kind of preparation method of α aza toroids compound | 贵州医科大学 | 2017-06-23 | — | — | CN | disclosed |