Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.30 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24846696 | 0.83 | PDPK1 (0.37) | PDPK1CES2CES1HTR1DMME | |
| SCHEMBL765949 | 0.83 | HTR1D (0.37) | HTR1DALDH1A1LMNAHTTHTR1B | |
| SCHEMBL84476 | 0.78 | LMNA (0.44) | PDPK1CES2CES1MMEALDH1A1 | |
| SCHEMBL21508221 | 0.78 | HTR1D (0.38) | HTR1DALDH1A1LMNAHTTHTR1B | |
| SCHEMBL18927431 | 0.75 | PDPK1 (0.40) | PDPK1CES2CES1MMEALDH1A1 | |
| SCHEMBL25027740 | 0.75 | LMNA (0.34) | PDPK1MAPTLMNAL3MBTL1TP53 | |
| SCHEMBL19243503 | 0.75 | S1PR3 (0.38) | ALDH1A1 | |
| SCHEMBL21513936 | 0.73 | HTR1D (0.42) | HTR1DALDH1A1HTT | |
| SCHEMBL10289693 | 0.73 | LMNA (0.38) | HTR1DALDH1A1LMNAHTTHTR1B | |
| SCHEMBL18929486 | 0.73 | HSP90AA1 (0.38) | HTR1DALDH1A1LMNAHTTTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11566001-B2 | Hepatitis B capsid assembly modulators | VenatoRx Pharmaceuticals, Inc. (US) | 2023-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11566001-B2 | Hepatitis B capsid assembly modulators | HAVCR2, COPB1, HDLBP | PDPK1 2915/4885CES2 2415/4885CES1 393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.