Bromide

Bromide

SCHEMBL2494675

C=C[n+]1ccccc1C.[Br-]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 0.31
NPC1 O15118 1/20 0.41
POLB P06746 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HDAC8 Q9BY41 2/20 0.39
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1164410 0.98
Hydrochloric Acid SCHEMBL585916 0.95 HDAC8 (0.39) NPC1POLBRAB9ASMN1; SMN2HDAC8
Iodide SCHEMBL2713208 0.95 HDAC8 (0.39) NPC1POLBRAB9ASMN1; SMN2HDAC8
SCHEMBL9289232 0.74
Hydrochloric Acid SCHEMBL2454796 0.73 NPC1 (0.36) NPC1POLBRAB9ASMN1; SMN2HDAC8
Bromide SCHEMBL9853476 0.72 HDAC8 (0.35) HDAC8
Hydrochloric Acid SCHEMBL11047633 0.71 NPC1 (0.35) NPC1POLBRAB9ASMN1; SMN2
SCHEMBL28731818 0.71 NPC1 (0.35) NPC1POLBRAB9ASMN1; SMN2TSHR
Ammonia Solution, Strong SCHEMBL28760022 0.70 NPC1 (0.34) NPC1POLBRAB9ASMN1; SMN2
SCHEMBL3319557 0.68 CHAT (0.45) NPC1RAB9ASMN1; SMN2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3370064-A1 REAGENT AND METHOD FOR MEASURING THROMBIN-ANTITHROMBIN COMPLEX LSI Medience Corporation (JP) 2018-09-05 EP claimed
US-20180238871-A1 REAGENT AND METHOD FOR MEASURING THROMBIN-ANTITHROMBIN COMPLEX PHC CORPORATION (JP) 2018-08-23 US claimed
CN-117990906-A Thrombin-antithrombin complex assay reagent and assay method 普和希株式会社 2024-05-07 CN disclosed
US-11378577-B2 Reagent and method for measuring thrombin-antithrombin complex LSI MEDIENCE CORPORATION (JP) 2022-07-05 US disclosed
US-11378577-B2 Reagent and method for measuring thrombin-antithrombin complex LSI MEDIENCE CORPORATION (JP) 2022-07-05 US disclosed
US-20190016909-A1 TEMPLATE SYNTHESIS OF POLYMERIC NANOMATERIALS BY INK-JET PRINTING UNIVERSITY OF NOTRE DAME DU LAC (US) 2019-01-17 US disclosed
US-10109387-B2 Transparent nanowire electrode comprising a functional organic layer FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2018-10-23 US disclosed
EP-3370064-A1 REAGENT AND METHOD FOR MEASURING THROMBIN-ANTITHROMBIN COMPLEX LSI Medience Corporation (JP) 2018-09-05 EP disclosed
US-20180238871-A1 REAGENT AND METHOD FOR MEASURING THROMBIN-ANTITHROMBIN COMPLEX PHC CORPORATION (JP) 2018-08-23 US disclosed
US-20180238871-A1 REAGENT AND METHOD FOR MEASURING THROMBIN-ANTITHROMBIN COMPLEX PHC CORPORATION (JP) 2018-08-23 US disclosed
WO-2017123660-A1 TEMPLATE SYNTHESIS OF POLYMERIC MATERIALS BY INKJET PRINTING UNIVERSITY OF NOTRE DAME DU LAC (US) 2017-07-20 WO disclosed
US-20160300637-A1 TRANSPARENT NANOWIRE ELECTRODE COMPRISING A FUNCTIONAL ORGANIC LAYER FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2016-10-13 US disclosed
US-8021716-B2 Polyelectrolyte-encapsulated pigments CLARIANT FINANCE (BVI) LIMITED (VG) 2011-09-20 US disclosed
US-20070224345-A1 Polyelectrolyte-encapsulated pigments CLARIANT INTERNATIONAL LTD 2007-09-27 US disclosed
US-7056554-B2 Production of polyelectrolyte capsules by surface precipitation MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2006-06-06 US disclosed
US-20040013738-A1 Encapsulation of liquid template particles MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFREN E.V. (DE) 2004-01-22 US disclosed
US-20030175517-A1 Production of polyelectrolyte capsules by surface precipitation MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2003-09-18 US disclosed