Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29098366 | 0.96 | HDAC8 (0.35) | HDAC8TP53 | |
| Iodide SCHEMBL11385773 | 0.96 | HDAC8 (0.35) | HDAC8TP53 | |
| Bromide SCHEMBL6834383 | 0.82 | KCNH2 (0.41) | HDAC8 | |
| Iodide SCHEMBL11395802 | 0.81 | HDAC8 (0.33) | HDAC8 | |
| SCHEMBL6533529 | 0.78 | KCNH2 (0.49) | — | |
| Iodide SCHEMBL11381499 | 0.78 | KCNH2 (0.41) | HDAC8 | |
| SCHEMBL362206 | 0.78 | HDAC8 (0.32) | HDAC8 | |
| SCHEMBL3661655 | 0.74 | CALM1 (0.41) | HDAC8TP53 | |
| Hydrochloric Acid SCHEMBL5688232 | 0.73 | CALM1 (0.39) | TP53 | |
| Bromide SCHEMBL2494675 | 0.72 | NPC1 (0.41) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276362-A | CHARGE TRANSFER COMPLEX | CATALYST RESEARCH CORPORATION (US) | 1981-06-30 | — | — | US | claimed |
| EP-0424703-A2 | Optical sensor | OLYMPUS OPTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |