Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9289232 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL585916 | 0.77 | HDAC8 (0.39) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11047633 | 0.76 | NPC1 (0.35) | NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL1164410 | 0.74 | — | — | |
| Bromide SCHEMBL2494675 | 0.73 | NPC1 (0.41) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| Iodide SCHEMBL2713208 | 0.73 | HDAC8 (0.39) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28731818 | 0.71 | NPC1 (0.35) | NPC1POLBRAB9ASMN1; SMN2TSHR | |
| Ammonia Solution, Strong SCHEMBL28760022 | 0.70 | NPC1 (0.34) | NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL3319557 | 0.68 | CHAT (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL339345 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227304-A1 | CONCENTRATED CONDITIONING COMPOSITIONS | UNILEVER IP HOLDINGS B.V. (NL) | 2023-11-30 | — | — | WO | claimed |
| WO-2023066502-A1 | WATER REDUCED COMPACT CONDITIONER COMPOSITION | WELLA GERMANY GMBH (DE) | 2023-04-27 | — | — | WO | claimed |
| WO-2023067173-A1 | WATER REDUCED COMPACT CONDITIONER COMPOSITION | WELLA GERMANY GMBH (DE) | 2023-04-27 | — | — | WO | claimed |
| US-6495243-B1 | Recording substrates for ink jet printing | XEROX CORPORATION | 2002-12-17 | — | — | US | claimed |
| US-6444294-B1 | MULTILAYER PHOTOGRAPHIC FILMS | XEROX CORPORATION | 2002-09-03 | — | — | US | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0615855-B1 | Recording sheets containing pyridinium and/or piperazinum compounds | XEROX CORP (US) | 1997-05-14 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| US-5441795-A | Piperazinium compounds | XEROX CORPORATION (US) | 1995-08-15 | — | — | US | claimed |
| EP-0615855-A1 | Recording sheets containing pyridinium and/or piperazinum compounds | XEROX CORPORATION (US) | 1994-09-21 | — | — | EP | claimed |
| US-4310510-A | Self administrable anti-fertility composition | SHERMAN KENNETH N | 1982-01-12 | — | — | US | claimed |
| US-4252787-A | CONTRACEPTIVES, PROGESTATIONAL ACTIVITY, STEROIDS | CAMBRIDGE RESEARCH AND DEVELOPMENT GROUP (US) | 1981-02-24 | — | — | US | claimed |
| US-20240238191-A1 | PERSONAL CARE COMPOSITION | THE PROCTER & GAMBLE COMPANY | 2024-07-18 | — | — | US | disclosed |
| WO-2024124105-A1 | PERSONAL CARE COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2024-06-13 | — | — | WO | disclosed |
| US-4105566-A | FIREPROOFING, BIOCIDAL ACTIVITY, AMMONIUM POLYPHOSPHATE, ORGANO-TIN COMPOUND | ALBRIGHT & WILSON LIMITED (GB) | 1978-08-08 | — | — | US | disclosed |
| US-4077890-A | Composition for treating fabrics, method for making and using the same | GRANUM INCORPORATED | 1978-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238191-A1 | PERSONAL CARE COMPOSITION | CUTA, POLR1C, POLN | NPC1 3898/4885POLB 11/4885RAB9A 4347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.