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SCHEMBL24948205

SCHEMBL24948205

c1ccc(-c2ccc(N(c3ccc(-c4c(-c5ccccc5)cccc4-n4c5ccccc5c5ccccc54)cc3)c3cccc(-c4cc5ccccc5c5ccccc45)c3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.33
▸ GPR84 Q9NQS5 2/20 0.33
▸ CYP11B1 P15538 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ MPI P34949 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24948169 0.96 MCL1 (0.34) ALOX5GPR84CYP11B1KDM4EMEN1
SCHEMBL24949303 0.93 ALOX5 (0.32) ALOX5GPR84CYP11B1
SCHEMBL24949655 0.93 GPR84 (0.32) ALOX5GPR84CYP11B1
SCHEMBL24948588 0.93 CYP11B1 (0.33) ALOX5GPR84CYP11B1KDM4EMEN1
SCHEMBL24948484 0.92 TDP1 (0.31) ALOX5
SCHEMBL26487991 0.92 HSD17B1 (0.33) ALOX5KDM4EMEN1ALDH1A1MAPT
SCHEMBL24949391 0.92 CYP11B1 (0.33) ALOX5GPR84CYP11B1KDM4EMEN1
SCHEMBL26489376 0.92 MCL1 (0.37) ALDH1A1
SCHEMBL26488240 0.91 HSD17B1 (0.34) ALOX5GPR84KDM4EMEN1ALDH1A1
SCHEMBL26487887 0.91 KDM4E (0.33) ALOX5GPR84KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023002447-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 — — WO disclosed
WO-2023003403-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 — — WO disclosed