Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.66 |
| ▸ | KDR | P35968 | 8/20 | 0.66 |
| ▸ | RET | P07949 | 4/20 | 0.66 |
| ▸ | KIF5B | P33176 | 3/20 | 0.66 |
| ▸ | FBP1 | P09467 | 2/20 | 0.66 |
| ▸ | CLK1 | P49759 | 2/20 | 0.66 |
| ▸ | AURKA | O14965 | 1/20 | 0.66 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.66 |
| ▸ | INSR | P06213 | 1/20 | 0.66 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.66 |
| ▸ | FLT4 | P35916 | 1/20 | 0.66 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.66 |
| ▸ | TEK | Q02763 | 1/20 | 0.66 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.66 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.66 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.66 |
| ▸ | SRC | P12931 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.62 |
| ▸ | LCK | P06239 | 3/20 | 0.61 |
| ▸ | FLT1 | P17948 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24950283 | 0.88 | KDR (0.85) | EGFRKDRRETKIF5BFBP1 | |
| SCHEMBL13497856 | 0.88 | EGFR (0.85) | EGFRKDRFBP1CLK1AURKA | |
| SCHEMBL25707230 | 0.84 | RET (0.68) | EGFRKDRRETKIF5BFBP1 | |
| SCHEMBL19220799 | 0.84 | KDR (0.73) | EGFRKDRRETKIF5BFBP1 | |
| SCHEMBL12846249 | 0.84 | EGFR (0.64) | EGFRKDRRETKIF5BFBP1 | |
| SCHEMBL19885272 | 0.83 | EGFR (0.64) | EGFRKDRRETKIF5BFBP1 | |
| SCHEMBL8871277 | 0.83 | EGFR (0.84) | EGFRKDRRETKIF5BFBP1 | |
| SCHEMBL5565204 | 0.81 | KDR (0.79) | EGFRKDRRETKIF5BCLK1 | |
| SCHEMBL15217642 | 0.81 | FBP1 (0.77) | EGFRKDRRETKIF5BFBP1 | |
| SCHEMBL19006946 | 0.81 | EGFR (0.81) | EGFRKDRRETKIF5BFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4122925-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | Medshine Discovery Inc. (CN) | 2023-01-25 | — | — | EP | disclosed |