Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | TOP1 | P11387 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12766811 | 0.88 | NTRK1 (0.54) | TERTNTRK1PLK3MEN1KMT2A | |
| SCHEMBL7574891 | 0.81 | NTRK1 (0.44) | TERTNTRK1PLK3MEN1KMT2A | |
| SCHEMBL11768754 | 0.80 | NTRK1 (0.74) | TERTNTRK1PLK3MEN1KMT2A | |
| SCHEMBL30704422 | 0.80 | NTRK1 (0.74) | TERTNTRK1PLK3MEN1KMT2A | |
| SCHEMBL7570053 | 0.80 | SOS1 (0.56) | TERTNTRK1PLK3MEN1KMT2A | |
| SCHEMBL7571223 | 0.80 | CYP19A1 (0.51) | TERTNTRK1PLK3MEN1KMT2A | |
| SCHEMBL15950982 | 0.77 | APP (0.61) | MEN1KMT2AKDM4EHSD17B10ALOX15 | |
| SCHEMBL9840758 | 0.75 | TOP1 (0.55) | TERTNTRK1PLK3MEN1KMT2A | |
| SCHEMBL30397993 | 0.73 | NTRK1 (0.64) | TERTNTRK1PLK3MEN1KMT2A | |
| SCHEMBL7572043 | 0.73 | NTRK1 (0.51) | TERTNTRK1PLK3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030296-B2 | Oestrogen-17-sulphamates as inhibitors of steroid sulphatase | STERIX LIMITED (GB) | 2011-10-04 | — | — | US | disclosed |
| US-20060281719-A1 | Oestrogen-17-sulphamates as inhibitors of steroid sulphatase | LLOYD POTTER BARRY V | 2006-12-14 | — | — | US | disclosed |
| US-7119081-B2 | Oestrogen-17-sulphamates as inhibitors of steroid sulphatase | STERIX LIMITED (GB) | 2006-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281719-A1 | Oestrogen-17-sulphamates as inhibitors of steroid sulphatase | STS, SULT1E1, HSD17B11 | TERT 764/4885NTRK1 4679/4885PLK3 1717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.