Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.74 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.74 |
| ▸ | TERT | O14746 | 1/20 | 0.51 |
| ▸ | TOP1 | P11387 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | APAF1 | O14727 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11768754 | 1.00 | NTRK1 (0.74) | NTRK1PLK3TERTTOP1MAPT | |
| SCHEMBL30397993 | 0.92 | NTRK1 (0.64) | NTRK1PLK3TERTTOP1MAPT | |
| SCHEMBL23621000 | 0.88 | NTRK1 (0.61) | NTRK1PLK3MAPTALDH1A1KDM4E | |
| SCHEMBL22247535 | 0.86 | NTRK1 (0.59) | NTRK1PLK3MAPTALDH1A1KDM4E | |
| SCHEMBL22541365 | 0.84 | NTRK1 (0.55) | NTRK1PLK3TERTTOP1MAPT | |
| SCHEMBL1520211 | 0.82 | NTRK1 (0.56) | NTRK1PLK3MAPTALDH1A1KDM4E | |
| SCHEMBL2495022 | 0.80 | TERT (0.54) | NTRK1PLK3TERTTOP1MAPT | |
| SCHEMBL12766811 | 0.80 | NTRK1 (0.54) | NTRK1PLK3TERTTOP1MAPT | |
| SCHEMBL7575236 | 0.78 | NTRK1 (0.55) | NTRK1PLK3MAPTCYP3A4KMT2A | |
| SCHEMBL30704420 | 0.76 | TTR (0.55) | NTRK1PLK3TERTTOP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543856-A1 | BENZOCARBAZOLE DERIVATIVES AS INHIBITORS OF DRP1 | Asha Therapeutics LLC (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023249965-A1 | BENZOCARBAZOLE DERIVATIVES AS INHIBITORS OF DRP1 | ASHA THERAPEUTICS LLC (US) | 2023-12-28 | — | — | WO | disclosed |