Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437460 | 0.88 | GAA (0.67) | GAAKDM4EALDH1A1GLAPOLB | |
| SCHEMBL23115272 | 0.86 | KMT2A (0.60) | GAAKDM4EALDH1A1GLAPOLB | |
| SCHEMBL3611257 | 0.85 | THRB (0.61) | GAAPOLBKMT2AMEN1THRB | |
| SCHEMBL6610000 | 0.84 | TSHR (0.49) | KDM4ETHRBMAPTNQO2MTNR1A | |
| SCHEMBL3594643 | 0.82 | TP53 (0.50) | GAAPOLBKMT2AMEN1THRB | |
| SCHEMBL24938760 | 0.81 | ALOX15 (0.59) | KDM4EALDH1A1GLAKMT2ASIRT1 | |
| SCHEMBL17793525 | 0.81 | ALDH1A1 (0.48) | GAAALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL734054 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1MAPTTP53 | |
| SCHEMBL3610150 | 0.80 | TP53 (0.48) | GAAKDM4EALDH1A1GLAPOLB | |
| SCHEMBL2267233 | 0.79 | NPC1 (0.49) | ALDH1A1KMT2ASIRT1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158152-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | MEDSHINE DISCOVERY INC. (CN) | 2023-05-25 | — | — | US | disclosed |
| EP-4122925-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | Medshine Discovery Inc. (CN) | 2023-01-25 | — | — | EP | disclosed |
| CN-109575342-A | A kind of synthetic method of novel photoactive dry film acrylic resin | 湖南鸿瑞新材料股份有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-109491205-A | A kind of Photosensitve resin composition and preparation method thereof | 湖南鸿瑞新材料股份有限公司 | 2019-03-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158152-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | PSMA6, PSMC1, PSMA1 | GAA 260/4885KDM4E 1251/4885ALDH1A1 4341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.