Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12963515 | 0.88 | MAPT (0.56) | HPGDLMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL1924747 | 0.87 | MAPT (0.57) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL2492317 | 0.86 | LMNA (0.44) | HPGDLMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL8443721 | 0.86 | MAPT (0.53) | HPGDLMNAMAPTALDH1A1GAA | |
| SCHEMBL31081617 | 0.85 | ABL1 (0.49) | HPGDLMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL22280833 | 0.84 | L3MBTL1 (0.60) | HPGDLMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL12995616 | 0.83 | MAPT (0.48) | HPGDMAPTALDH1A1ADRA2AADRA2B | |
| SCHEMBL9330354 | 0.83 | ABL1 (0.51) | HPGDLMNAHTTSMN1; SMN2BCHE | |
| SCHEMBL24120583 | 0.82 | MAPT (0.43) | HPGDLMNAMAPTALDH1A1KDM4E | |
| SCHEMBL18235897 | 0.82 | LOXL2 (0.44) | HPGDMAPTALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974699-A | Preparation method of aromatic diamine | 江苏湘园化工有限公司 | 2023-04-18 | — | — | CN | disclosed |
| EP-2380567-B1 | MELANIN PRODUCTION INHIBITOR | POLA CHEM IND INC (JP) | 2019-01-16 | — | — | EP | disclosed |
| EP-3009123-A1 | MELANIN PRODUCTION INHIBITOR | Pola Chemical Industries Inc. (JP) | 2016-04-20 | — | — | EP | disclosed |
| US-20150328107-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2015-11-19 | — | — | US | disclosed |
| EP-2845587-A2 | Melanin production inhibitor | Pola Chemical Industries Inc. (JP) | 2015-03-11 | — | — | EP | disclosed |
| US-20140363389-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-12-11 | — | — | US | disclosed |
| US-8846012-B2 | Melanin production inhibitor | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-09-30 | — | — | US | disclosed |
| EP-2380567-A1 | MELANIN PRODUCTION INHIBITOR | Pola Chemical Industries Inc. (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-20110243865-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2011-10-06 | — | — | US | disclosed |
| EP-0336391-B1 | Reversibly color-changeable materials | TEIJIN LTD (JP) | 1994-01-26 | — | — | EP | disclosed |
| US-5068062-A | Crosslinked resin containing 4,4*-diaminodiphenylmethane units with the amine quaternized and an electrolytic material | TEIJIN LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0336391-A2 | Reversibly color-changeable materials | TEIJIN LIMITED (JP) | 1989-10-11 | — | — | EP | disclosed |
| US-3943158-A | POLYURETHANE MONOMERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110243865-A1 | MELANIN PRODUCTION INHIBITOR | TYR, F12, TH | HPGD 1749/4885LMNA 2547/4885HTT 1217/4885 |
| US-20150328107-A1 | MELANIN PRODUCTION INHIBITOR | TYR, MC1R, F12 | HPGD 1563/4885LMNA 2843/4885HTT 946/4885 |
| US-20140363389-A1 | MELANIN PRODUCTION INHIBITOR | TYR, F12, MC1R | HPGD 1618/4885LMNA 2187/4885HTT 989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.