Valethamate

Valethamate

SCHEMBL249537

CCC(C)C(C(=O)OCC[N+](C)(CC)CC)c1ccccc1

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 9/20 0.97
CHRM2 P08172 8/20 0.97
CHRM3 P20309 7/20 0.97
CHRM4 P08173 6/20 0.97
CYP2D6 P10635 3/20 0.97
CHRM5 P08912 1/20 0.97
SIGMAR1 Q99720 1/20 0.97
SCN1A P35498 2/20 0.48
SCN2A Q99250 2/20 0.48
SCN3A Q9NY46 2/20 0.48
KCNH2 Q12809 2/20 0.44
LMNA P02545 2/20 0.44
CYP1A2 P05177 2/20 0.44
KMT2A Q03164 2/20 0.44
SLC6A3 Q01959 1/20 0.43
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valethamate SCHEMBL249506 0.99 CHRM1 (1.00) CHRM1CHRM2CHRM3CHRM4CYP2D6
Valethamate SCHEMBL10011072 0.96 CHRM1 (0.95) CHRM1CHRM2CHRM3CHRM4CYP2D6
SCHEMBL4964029 0.76 KMT2A (0.70) CHRM1CHRM2CHRM3CHRM4CYP2D6
Bromide SCHEMBL9325014 0.75 CHRM1 (0.60) CHRM1CHRM2CHRM3CHRM4CYP2D6
SCHEMBL7878308 0.73 CHRM2 (0.58) CHRM1CHRM2CHRM3CHRM4CYP2D6
SCHEMBL7713699 0.73 CHRM1 (0.56) CHRM1CHRM2CHRM3CHRM4CYP2D6
SCHEMBL13532000 0.73 CHRM1 (0.60) CHRM1CHRM2CHRM3CHRM4CYP2D6
SCHEMBL23872457 0.72 CYP2D6 (0.61) CHRM1CHRM2CHRM3CHRM4CYP2D6
SCHEMBL4921518 0.72 CYP2D6 (0.61) CHRM1CHRM2CHRM3CHRM4CYP2D6
SCHEMBL499471 0.72 CYP2D6 (0.61) CHRM1CHRM2CHRM3CHRM4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4679087-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 EP claimed
CN-115081590-B Short-term wind speed prediction method based on complex value acceleration algorithm 苏州大学 2025-05-02 CN claimed
CN-118363792-B Mass information storage system of transformer substation 国网山东省电力公司沂水县供电公司 2025-01-21 CN claimed
CN-118363792-A Mass information storage system of transformer substation 国网山东省电力公司沂水县供电公司 2024-07-19 CN claimed
CN-117908891-B Robot flow automation-oriented bottom-up translation method 山东大学 2024-07-02 CN claimed
CN-114116330-B Server performance testing method, system, terminal and storage medium 苏州浪潮智能科技有限公司 2024-05-24 CN claimed
CN-113901995-B Clustering method and system for environmental noise data 广东奥博信息产业股份有限公司 2024-04-12 CN claimed
CN-112734934-B STL model 3D printing slicing method based on intersecting edge mapping 嘉兴学院 2023-12-01 CN claimed
CN-116738373-A Quick and efficient quantized item set mining method based on length constraint 西安电子科技大学 2023-09-12 CN claimed
CN-116413762-A Gas ionization chamber detection system and method for pulse beam current of laser proton accelerator 北京大学 2023-07-11 CN claimed
CN-113268807-B Finite particle method-based disaster simulation distributed computing method for building group 汕头大学 2022-02-18 CN claimed
CN-114047767-A Robot jumping point searching algorithm based on artificial potential field method 山东建筑大学 2022-02-15 CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-1273301-B1 Pharmaceutical preparations based on active ingredients susceptible to illicit administration ALTERGON SA (CH) 2006-09-06 EP claimed
CN-1520818-A Cholinesterase inhibitor pharmaceutical composition for senile dementia ɽ����Ҷ��Ȼҩ���о��������޹�˾ 2004-08-18 CN claimed