Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 known ✓ | P20309 | 5/20 | 0.60 |
| ▸ | CHRM2 known ✓ | P08172 | 4/20 | 0.60 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4964029 | 0.78 | KMT2A (0.70) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| Valethamate SCHEMBL249537 | 0.75 | CHRM1 (0.97) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| Valethamate SCHEMBL10011072 | 0.74 | CHRM1 (0.95) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| Valethamate SCHEMBL249506 | 0.74 | CHRM1 (1.00) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| SCHEMBL7878308 | 0.72 | CHRM2 (0.58) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| SCHEMBL10443302 | 0.72 | CHRM2 (0.52) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| SCHEMBL23872457 | 0.71 | CYP2D6 (0.61) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| SCHEMBL4921518 | 0.71 | CYP2D6 (0.61) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| SCHEMBL499471 | 0.71 | CYP2D6 (0.61) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| SCHEMBL7713699 | 0.69 | CHRM1 (0.56) | CHRM1CHRM3CHRM2CHRM4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10910674-B2 | Additive for increasing lifespan of rechargeable zinc-anode batteries | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW NEW YORK (US) | 2021-02-02 | — | — | US | claimed |
| US-20180316064-A1 | Additive for Increasing Lifespan of Rechargeable Zinc-Anode Batteries | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW NEW YORK (US) | 2018-11-01 | — | — | US | claimed |
| US-20260088352-A1 | Heterocyclic Electrolyte Additives for Rechargeable Metal Batteries | U S ARMY DEVCOM ARMY RES LABORATORY (US) | 2026-03-26 | — | — | US | disclosed |
| US-20230223595-A1 | Heterocyclic Electrolyte Additives for Rechargeable Metal Batteries | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2023-07-13 | — | — | US | disclosed |
| US-10910674-B2 | Additive for increasing lifespan of rechargeable zinc-anode batteries | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW NEW YORK (US) | 2021-02-02 | — | — | US | disclosed |
| US-20180316064-A1 | Additive for Increasing Lifespan of Rechargeable Zinc-Anode Batteries | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW NEW YORK (US) | 2018-11-01 | — | — | US | disclosed |
| US-5308735-A | Aromatic-aldehyde resins, improved solubility | NIPPON PAINT CO., LTD. (JP) | 1994-05-03 | — | — | US | disclosed |
| EP-0540016-A1 | Photosensitive resin and resin composition for lithographic printing | Nippon Paint Co., Ltd. (JP) | 1993-05-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260088352-A1 | Heterocyclic Electrolyte Additives for Rechargeable Metal Batteries | CA3, CA1, HCN1 | CHRM3 967/4885CHRM2 605/4885SIGMAR1 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.