Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715661 | 0.83 | PTGS2 (0.38) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| SCHEMBL7878782 | 0.82 | MEN1 (0.49) | KMT2AMEN1GAAKDM4EL3MBTL1 | |
| SCHEMBL7878308 | 0.82 | CHRM2 (0.58) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| SCHEMBL7876959 | 0.81 | CHRM1 (0.52) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| SCHEMBL4964029 | 0.76 | KMT2A (0.70) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| Valethamate SCHEMBL249537 | 0.73 | CHRM1 (0.97) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| SCHEMBL23872457 | 0.72 | CYP2D6 (0.61) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| SCHEMBL4921518 | 0.72 | CYP2D6 (0.61) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| SCHEMBL499471 | 0.72 | CYP2D6 (0.61) | CHRM1CHRM3CHRM2CHRM4CYP2D6 | |
| SCHEMBL8448318 | 0.72 | LMNA (0.54) | CYP2D6KMT2AMEN1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376548-B1 | FUNGICIDES; HERBICIDES; INSECTICIDES | ROHM AND HAAS COMPANY | 2002-04-23 | — | — | US | disclosed |
| WO-2001056358-A2 | ENHANCED PROPERTIED PESTICIDES | ROHM AND HAAS COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |