Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TYMP | P19971 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | MST1R | Q04912 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28891458 | 0.83 | KDM4E (0.42) | ALDH1A1TYMPKDM4EPIM1CHEK1 | |
| SCHEMBL5801644 | 0.73 | ALDH1A1 (0.64) | ALDH1A1LMNAHTTMAPTDPYD | |
| SCHEMBL6535602 | 0.72 | MAOB (0.44) | ALDH1A1TYMPKDM4EPIM1CHEK1 | |
| SCHEMBL5069269 | 0.71 | NPC1 (0.49) | ALDH1A1KDM4EPIM1CHEK1HPGD | |
| SCHEMBL1981532 | 0.70 | LTK (0.56) | ALDH1A1TYMPKDM4EPIM1CHEK1 | |
| SCHEMBL8936641 | 0.70 | ALDH1A1 (0.47) | ALDH1A1LMNAHTTKMT2AMAPT | |
| SCHEMBL30709633 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KDM4EPIM1HPGDLMNA | |
| SCHEMBL3553811 | 0.70 | ATAD2 (0.50) | ALDH1A1LMNAHTTMAPTDPYD | |
| SCHEMBL27817299 | 0.70 | PARP1 (0.45) | ALDH1A1TYMPKDM4EPIM1CHEK1 | |
| SCHEMBL3485414 | 0.69 | ALDH1A1 (1.00) | ALDH1A1TYMPKDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102441170-A | Methods for administering DPD inhibitors in combination with 5-FU and 5-FU prodrugs | ADHEREX TECHNOLOGIES INC | 2012-05-09 | — | — | CN | claimed |
| CN-101068549-A | Methods of administering DPD inhibitors in combination with 5-FU and 5-FU prodrugs | ADHEREX TECHNOLOGIES INC (CA) | 2007-11-07 | — | — | CN | claimed |
| WO-2007122634-A2 | PYRIMIDINEDIONES AS TYROSINE KINASE INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2007-11-01 | — | — | WO | claimed |
| WO-2006076102-A2 | FLUORESCENT NUCLEOSIDE ANALOGS THAT MIMIC NATURALLY OCCURRING NUCLEOSIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-07-20 | — | — | WO | claimed |
| EP-3728237-B1 | SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-09 | — | — | EP | disclosed |
| CN-111705329-B | Electrochemical synthesis method of 5-arylthio uracil compound | 湖南科技学院 | 2021-07-02 | — | — | CN | disclosed |
| CN-111705329-A | Electrochemical synthesis method of 5-arylthio uracil compound | 湖南科技学院 | 2020-09-25 | — | — | CN | disclosed |
| EP-2007750-B1 | AZABICYCLO [3. 1. 0] HEXYL DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS | GLAXO GROUP LTD (GB) | 2013-08-21 | — | — | EP | disclosed |
| CN-102441170-A | Methods for administering DPD inhibitors in combination with 5-FU and 5-FU prodrugs | ADHEREX TECHNOLOGIES INC | 2012-05-09 | — | — | CN | disclosed |
| US-8030322-B2 | Spirocompounds useful as modulators for dopamine D3 receptors | GLAXO GROUP LIMITED (GB) | 2011-10-04 | — | — | US | disclosed |
| US-8030322-B2 | Spirocompounds useful as modulators for dopamine D3 receptors | GLAXO GROUP LIMITED (GB) | 2011-10-04 | — | — | US | disclosed |
| US-8030322-B2 | Spirocompounds useful as modulators for dopamine D3 receptors | GLAXO GROUP LIMITED (GB) | 2011-10-04 | — | — | US | disclosed |
| US-20050037478-A1 | Crystal structure of glutamate racemase (MurI) | ASTRAZENECA AB (SE) | 2005-02-17 | — | — | US | disclosed |
| WO-2004061097-A2 | CRYSTAL STRUCTURE OF GLUTAMATE RACEMASE (MURI) | ASTRAZENECA AB (SE) | 2004-07-22 | — | — | WO | disclosed |
| US-5576429-A | HUMAN T-CELL LEUKEMIA/LYMPHOMA VIRICIDE; ANTITUMOR AGENT | MEDIVIR AB (SE) | 1996-11-19 | — | — | US | disclosed |
| EP-0357571-B1 | Pyrimidine nucleosides | MEDIVIR AB (SE) | 1996-04-03 | — | — | EP | disclosed |
| EP-0691333-A2 | Pyrimidine derivatives, process for their preparation and their use as precursors | Medivir Aktiebolag (SE) | 1996-01-10 | — | — | EP | disclosed |
| US-5440040-A | Drug for Aids therapy; viricides | MEDIVIR AB (SE) | 1995-08-08 | — | — | US | disclosed |
| EP-0357571-A2 | Pyrimidine nucleosides | Medivir Aktiebolag (SE) | 1990-03-07 | — | — | EP | disclosed |
| WO-1989012061-A1 | PYRIMIDINE NUCLEOSIDES AND INTERMEDIATES | MEDIVIR AB (SE) | 1989-12-14 | — | — | WO | disclosed |